Abstract:
The present invention relates to a method for manufacturing an Allomyrina dichotoma extract having anti-obesity effect and an anti-obesity composition including the same. The method for manufacturing an Allomyrina dichotoma extract having anti-obesity effect of the present invention is characterized by comprising the steps of: (a) grinding freeze-dried Allomyrina dichotoma; (b) mixing the ground Allomyrina dichotoma and a solvent to manufacture an Allomyrina dichotoma mixture; (c) refining the Allomyrina dichotoma mixture with an ultrasoniator; and (d) performing centrifugation of the ground Allomyrina dichotoma mixture and collecting and filtering a supernatant. The anti-obesity composition including the Allomyrina dichotoma extract as an active ingredient according to the present invention has no side effect, and not only has excellent stability, but also has anti-obesity effect to be used as an agent for preventing and treating obesity and obesity-related diseases.
Abstract:
본 발명은 꽃무지를 유효성분으로 포함하는 알츠하이머성 치매 예방 및 치료용 약학 조성물 및 알츠하이머성 치매 개선용 식품조성물에 관한 것이다. 보다 상세하게는 베타-세크리테이즈(β-Secretase)활성 억제를 통해 알츠하이머성 치매 저해 효과를 갖는 꽃무지를 유효성분으로 포함하는 알츠하이머성 치매 예방 및 치료용 약학 조성물 및 알츠하이머성 치매 개선용 식품조성물에 관한 것이다. 본 발명에 의해, 고분자의 합성저해제가 통과하지 못하는 혈뇌장벽(Blood brain barrier)을 통과할 수 있게 되어, 항치매 선도물질 개발에서도 유리할 것으로 기대된다.