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公开(公告)号：KR1020150050631A
公开(公告)日：2015-05-11
申请号：KR1020130129261
申请日：2013-10-29
Applicant: 대한민국(농촌진흥청장) , 대구한의대학교산학협력단
Abstract: 본발명은코프리신펩타이드유도체 CopA3를함유하는항염증화장료및 피부외용제조성물에관한것으로, 더욱상세하게는염증으로유발되는피부질환의예방및 개선을위한코프리신펩타이드유도체 CopA3를함유하는항염증화장료및 피부외용제조성물에관한것이다. 본발명에따른항염증화장료조성물및 피부외용제조성물은서열번호 1로표시되는아미노산서열을가지는코프리신펩타이드유도체 CopA3를함유하는것을특징으로한다. 상기항염증화장료조성물및 피부외용제조성물은초기-염증성인자(pro-inflammatory mediator)의생성및 발현억제를유도함으로써염증으로유발되는피부질환의예방및 개선에효과적이다.
Abstract translation: 本发明涉及化妆品组合物和抗皮肤病学组合物。本发明涉及抗炎化妆品组合物和含有复合蛋白肽衍生物CopA3的皮肤病学组合物，更具体地，涉及抗炎化妆品组合物和皮肤病学 含有共感染肽衍生物CopA3的组合物，用于预防和减轻由炎症引起的皮肤疾病。 根据本发明，抗炎化妆品和皮肤病学组合物包含含有表示为序列号1的氨基酸序列的共立克斯肽衍生物CopA3。抗炎化妆品和皮肤病学组合物有效预防和减轻由炎症引起的皮肤疾病 通过诱导抑制促炎介质的产生和表达。
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公开(公告)号：KR1020150050627A
公开(公告)日：2015-05-11
申请号：KR1020130129234
申请日：2013-10-29
Applicant: 대한민국(농촌진흥청장) , 대구한의대학교산학협력단
CPC classification number: A61K8/64
Abstract: 본발명은무당벌레유충유래신규펩타이드를함유하는항염증화장료및 피부외용제조성물에관한것으로, 더욱상세하게는염증으로유발되는피부질환의예방및 개선을위한무당벌레유충유래신규펩타이드를함유하는항염증화장료및 피부외용제조성물에관한것이다. 본발명에따른항염증화장료조성물및 피부외용제조성물은서열번호 1로표시되는아미노산서열을가지는무당벌레유충유래신규펩타이드 HaGF를함유하는것을특징으로한다. 상기항염증화장료조성물및 피부외용제조성물은초기-염증성인자(pro-inflammatory mediator)의생성및 발현억제를유도함으로써염증으로유발되는피부질환의예방및 개선에효과적이다.
Abstract translation: 本发明涉及一种抗炎化妆品组合物和含有源自Harmonia axyridis幼虫的新肽的皮肤病学组合物，更具体地，涉及抗炎化妆品组合物和含有源自Harmonia axyridis幼虫的新肽的皮肤病学组合物，用于预防 并减轻炎症引起的皮肤病。 根据本发明，抗炎化妆品和皮肤病学组合物包含源自Harmonia axyridis幼虫的新肽HaGF，其含有表示为序列号1的氨基酸序列。抗炎化妆品和皮肤病学组合物有效预防和缓解皮肤 由炎症引起的疾病，通过诱导抑制生成和促炎介质的表达。
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公开(公告)号：KR101557788B1
公开(公告)日：2015-10-07
申请号：KR1020130129234
申请日：2013-10-29
Applicant: 대한민국(농촌진흥청장) , 대구한의대학교산학협력단
Abstract: 본발명은무당벌레유충유래신규펩타이드를함유하는항염증화장료및 피부외용제조성물에관한것으로, 더욱상세하게는염증으로유발되는피부질환의예방및 개선을위한무당벌레유충유래신규펩타이드를함유하는항염증화장료및 피부외용제조성물에관한것이다.본발명에따른항염증화장료조성물및 피부외용제조성물은서열번호 1로표시되는아미노산서열로구성되는서열로구성되는유래신규펩타이드 HaGF를함유하는것을특징으로한다. 상기항염증화장료조성물및 피부외용제조성물은초기-염증성인자(pro-inflammatory mediator)의생성및 발현억제를유도함으로써염증으로유발되는피부질환의예방및 개선에효과적이다.
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公开(公告)号：KR101603951B1
公开(公告)日：2016-03-17
申请号：KR1020130129442
申请日：2013-10-29
Applicant: 대한민국(농촌진흥청장) , 대진대학교 산학협력단
Abstract: 본발명은룸브리쿠신펩타이드를유효성분으로함유하는신경세포성장조절용조성물에관한것이다. 본발명에서는서열번호 1의아미노산배열로이루어지며, 신경세포의성장을촉진하는조절자인룸브리쿠신펩타이드(lumbricusin peptide)를유효성분으로함유하는퇴행성신경질환의치료용조성물을제공하는것이특징이다. 본발명에의해, 별다른부작용없이신경세포성장과증식을촉진하거나세포사멸과정을억제할수 있는새로운신경세포성장조절용조성물이제공될수 있어, 퇴행성신경질환의치료를위한비용이저렴하면서부작용이없는새로운치료제의개발가능성을제공한다는등의현저한효과를제공할수 있게된다.
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公开(公告)号：KR101535895B1
公开(公告)日：2015-07-16
申请号：KR1020120131512
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은코프리신펩타이드 CopA3를유효성분으로포함하는암 질환예방및 치료용약학적조성물에관한것으로보다상세하게는위암관련치료를위한조성물을개발하기위하여위암세포주에항암활성검정을통하여개발된코프리신펩타이드 CopA3를유효성분으로포함하는암 질환예방및 치료용약학적조성물에관한것이다. 본발명의코프리신펩타이드 CopA3는항암활성을갖고있고, 위암세포주에서세포증식억제효과가우수하기때문에암 질환예방및 치료용약학적조성물로이용하는데효과적이다.
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Patent Agency Ranking
公开(公告)号：KR1020140115774A
公开(公告)日：2014-10-01
申请号：KR1020130030848
申请日：2013-03-22
Applicant: 대한민국(농촌진흥청장)
Abstract: The present invention relates to an antimicrobial or antifungal composition comprising peptides isolated from Lumbricus terrestris as an active ingredient and, more specifically, to peptides having an amino acid sequence of sequence number 1, polynucleotide having a base sequence which encodes the peptides, and a use thereof. The peptide having an amino acid sequence of sequence number 1 according to the present invention, has an antimicrobial or antifungal activity and is nontoxic for red blood cells of a human, thereby being useful as an antimicrobial pharmaceutical composition, an antifungal pharmaceutical composition, and a preserving agent composition.
Abstract translation: 本发明涉及一种抗微生物或抗真菌组合物，其包含从天竺葵分离的肽作为活性成分，更具体地，涉及具有序列号1的氨基酸序列的肽，具有编码肽的碱基序列的多核苷酸，以及使用 它们。 具有本发明的序列号1的氨基酸序列的肽具有抗微生物或抗真菌活性，对人的红细胞无毒，因此可用作抗微生物药物组合物，抗真菌药物组合物和 防腐剂组合物。
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公开(公告)号：KR101444256B1
公开(公告)日：2014-09-26
申请号：KR1020130039756
申请日：2013-04-11
Applicant: 대한민국(농촌진흥청장)
IPC: C12N15/12 , C07K14/435 , A61K38/17 , A61P31/04
CPC classification number: Y02A50/473
Abstract: The present invention relates to a novel Scolopendrasin III peptide isolated from Scolopendra subspinipes and a composition thereof. The present invention provides a novel gene (sequence number 1) of an antibacterial and antifungal peptide isolated from Scolopendra subspinipes, or amino acid (sequence number 2) deducted from the gene, and a peptide (sequence number 3) synthesized from the amino acid. The novel Scolopendrasin III peptide isolated from Scolopendra subspinipes and a composition thereof are provided by the present invention. Accordingly, provided are antibiotics, food preservatives, cosmetic preservatives, medicines, etc. which are free from cytotoxicity and are safe for the human body while showing excellent antibacterial activity and antifungal activity.
Abstract translation: 本发明涉及从Scolopendra subspinipes分离的新型Scolopendrasin III肽及其组合物。 本发明提供从Scolopendra subspinipes分离的抗菌和抗真菌肽或从该基因中扣除的氨基酸（序列号2）的新基因（序列号1）和从该氨基酸合成的肽（序列号3）。 从Scolopendra subspinipes分离的新型Scolopendrasin III肽及其组合物由本发明提供。 因此，提供了没有细胞毒性的抗生素，食品防腐剂，化妆品防腐剂，药物等，同时具有优异的抗菌活性和抗真菌活性。
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公开(公告)号：KR1020140065690A
公开(公告)日：2014-05-30
申请号：KR1020120131512
申请日：2012-11-20
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은코프리신펩타이드 CopA3를유효성분으로포함하는암 질환예방및 치료용약학적조성물에관한것으로보다상세하게는위암관련치료를위한조성물을개발하기위하여위암세포주에항암활성검정을통하여개발된코프리신펩타이드 CopA3를유효성분으로포함하는암 질환예방및 치료용약학적조성물에관한것이다. 본발명의코프리신펩타이드 CopA3는항암활성을갖고있고, 위암세포주에서세포증식억제효과가우수하기때문에암 질환예방및 치료용약학적조성물로이용하는데효과적이다.
Abstract translation: 本发明涉及一种药物组合物，其包含作为预防和治疗癌症疾病的活性成分的共立克斯肽CopA3，更具体地，涉及一种药物组合物，其包含作为预防和治疗癌症疾病的有效成分的共共兴性肽CopA3， 胃癌细胞系中的抗癌活性验证，以开发用于胃癌相关治疗的组合物。 本发明的共立克斯肽CopA3具有抗癌活性，对于抑制胃癌细胞系的细胞增殖具有优异的作用，可以有效地用作预防和治疗癌症疾病的药物组合物。
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公开(公告)号：KR101510315B1
公开(公告)日：2015-04-10
申请号：KR1020130072199
申请日：2013-06-24
Applicant: 대한민국(농촌진흥청장)
Abstract: 본발명은멜라닌생성억제및 주름개선용화장료조성물에관한것이다. 본발명의멜라닌생성억제및 주름개선용화장료조성물은왕지네()추출물을유효성분으로포함하는것이특징이다. 본발명에의해, 세포독성을일으키지않으면서, 티로시나제(tyrosinase)의글리코실화(glycosylation)반응을방해하여멜라닌생성을효과적으로억제하는멜라닌생성억제용및 엘라스타아제(elastase) 저해하는주름개선용화장료조성물이제공된다.
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公开(公告)号：KR101444261B1
公开(公告)日：2014-09-29
申请号：KR1020130039757
申请日：2013-04-11
Applicant: 대한민국(농촌진흥청장)
IPC: C12N15/12 , C07K14/435 , A61K38/17 , A61P31/04
CPC classification number: Y02A50/473
Abstract: The present invention relates to a novel Scolopendrasin I peptide isolated from Scolopendra subspinipes and a composition thereof. The present invention provides a novel gene (sequence number 1) of an antibacterial and antifungal peptide isolated from Scolopendra subspinipes, or amino acid (sequence number 2) deducted from the gene, and a peptide (sequence number 3) synthesized from the amino acid. The novel Scolopendrasin I peptide isolated from Scolopendra subspinipes and a composition thereof are provided by the present invention. Accordingly, provided are antibiotics, food preservatives, cosmetic preservatives, medicines, etc. which are free from cytotoxicity and are safe for the human body while showing excellent antibacterial activity and antifungal activity.
Abstract translation: 本发明涉及一种分离自Scolopendra subspinipes的新型Scolopendrasin I肽及其组合物。 本发明提供从Scolopendra subspinipes分离的抗菌和抗真菌肽或从该基因中扣除的氨基酸（序列号2）的新基因（序列号1）和从该氨基酸合成的肽（序列号3）。 从Scolopendra subspinipes分离的新型Scolopendrasin I肽及其组合物由本发明提供。 因此，提供了没有细胞毒性的抗生素，食品防腐剂，化妆品防腐剂，药物等，同时具有优异的抗菌活性和抗真菌活性。
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