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公开(公告)号：KR1020110083917A
公开(公告)日：2011-07-21
申请号：KR1020100003899
申请日：2010-01-15
Applicant: 대한민국(문화재청 국립문화재연구소장)
IPC: A61K36/8965 , A61P29/00
Abstract: PURPOSE: A composition containing a fraction prepared from Asparagus cochinchinensis extract for preventing and treating inflammatory diseases is provided to suppress generation or secretion of TNF-alpha and IL-1 beta. CONSTITUTION: A composition for preventing and treating inflammatory disease contains a fraction as an active ingredient, prepared by fractioning Asparagus cochinchinensis extract with an organic solvent. The Asparagus cochinchinensis extract is isolated using water, low alcohol of C1-C4, or mixture solvent. The low alcohol is ethanol or methanol. The fraction is a n-hexane fraction, methylene chloride fraction, ethylacetate fraction, n-butanol fraction, or water fraction. A health food, functional feed additive, and cosmetic composition for preventing and treating inflammatory diseases contains the fraction as an active ingredient.
Abstract translation: 目的：提供含有用于预防和治疗炎性疾病的芦笋提取物制备的级分的组合物，以抑制TNF-α和IL-1β的产生或分泌。 构成：用于预防和治疗炎性疾病的组合物含有作为活性成分的级分，其通过用有机溶剂分馏芦笋提取物制备。 使用水，C1-C4的低醇或混合溶剂分离芦笋co ensis提取物。 低级醇是乙醇或甲醇。 馏分为正己烷馏分，二氯甲烷馏分，乙酸乙酯馏分，正丁醇馏分或水馏分。 用于预防和治疗炎性疾病的保健食品，功能性饲料添加剂和化妆品组合物含有该级分作为活性成分。
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公开(公告)号：KR101207239B1
公开(公告)日：2012-12-12
申请号：KR1020100003899
申请日：2010-01-15
Applicant: 대한민국(문화재청 국립문화재연구소장)
IPC: A61K36/8965 , A61P29/00
Abstract: 본발명은천문동() 추출물로부터제조한분획물을유효성분으로함유하는염증성질환의예방및 치료용조성물에관한것으로서, 더욱상세하게는, 천문동추출물을유기용매로분획하여제조한분획물은염증성사이토카인인인터루킨-1&bgr;(interleukin-1&bgr;, IL-1&bgr;) 및종양괴사인자-α(tumor necrosis factor-α, TNF-α)의생산또는분비를억제하는세포독성이없는안전한물질이므로, 염증성질환의예방또는치료를위한조성물의유효성분으로서유용하게사용할수 있다.
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