公开(公告)号：KR101354915B1

公开(公告)日：2014-01-24

申请号：KR1020130010256

申请日：2013-01-30

Applicant: 동신대학교산학협력단

Inventor： 박경목 ,  정대현 ,  김수정

IPC: C07K5/08 ,  A61K8/64 ,  A61Q19/02 ,  A61Q19/08

Abstract: The present invention relates to galloyl-peptide which has excellent stability at alternating temperatures, antioxidant activity, whitening activity, and anti-inflammatory activity and a cosmetic external preparation composition for skins using the same. According to the present invention, a manufacturing method for galloyl-peptide which is stable at alternating temperatures and a cosmetic external preparation composition for skins using the same are provided. The galloyl-peptide of the present invention has excellent stability at alternating temperatures when compared with peptide used in the manufacturing of the galloyl-peptide. The cosmetic external preparation composition for skins using the galloyl-peptide can be manufactured into cosmetics, chemicals, and soaps.

Abstract translation: 本发明涉及在交替温度，抗氧化活性，增白活性和抗炎活性方面具有优异稳定性的galloyl-肽，以及使用它们的外用化妆品外用剂组合物。 根据本发明，提供了在交替温度下稳定的酰基肽的制造方法和使用其的用于皮肤的美容外用剂组合物。 与用于制备酰基肽的肽相比，本发明的galloyl-peptide在交替的温度下具有优异的稳定性。 可以将化妆品，化学品和肥皂制成用于使用草酰基肽的皮肤的美容外用制剂组合物。

公开(公告)号：KR101478520B1

公开(公告)日：2015-01-02

申请号：KR1020140008870

申请日：2014-01-24

Applicant: 동신대학교산학협력단

Inventor： 박경목 ,  정대현 ,  김수정 ,  임창일 ,  성지연

IPC: C07K19/00 ,  C07K5/08 ,  A61K8/64

Abstract: 본 발명은 피부 안전성이 향상된 캡사이신-펩타이드 및 이를 이용한 피부 외용제 조성물을 개시한다. 구체적으로 본 발명은 캡사이신에 Arg-Gly-Asp(RGD), Glu-Cys-Gly(ECG) 또는 Gly-His-Lys(GHK)를 도입함으로써 얻어지는 피부 안정성이 향상된 캡사이신 펩타이드와 이를 이용한 피부 외용제 조성물을 개시한다.

Abstract translation: 在本发明中公开了具有改善的皮肤安全性的辣椒素肽，以及使用该辣椒素外用于皮肤的组合物。 具体地说，本发明中公开了通过将Arg-Gly-Asp（RGD），Glu-Cys-Gly（ECG）或Gly-His-Lys（GHK）在辣椒素中应用而获得的皮肤安全性提高的辣椒素肽 ，以及使用该组合物外用于皮肤的组合物。