公开(公告)号：KR100861730B1

公开(公告)日：2008-10-06

申请号：KR1020070033927

申请日：2007-04-06

Applicant: 무안군

Inventor： 박성규 ,  장문석 ,  박완수 ,  양웅모 ,  김도림 ,  박은화 ,  김원남 ,  오지훈 ,  심경준 ,  김휴영 ,  윤지원 ,  고은빛 ,  최문정 ,  김홍렬

IPC: A61K36/62 ,  A61P25/28

CPC classification number: A61K36/62 ,  A23V2200/322 ,  A61K2236/333

Abstract: An extract of Nelumbinis Semen is provided to show an effect of improving memory and learning ability and an effect of increasing brain cell proliferation during passive avoidance tests of a mouse, thereby being usefully used as a composition for preventing and treating cognitive impairment related diseases. A pharmaceutical composition for preventing and treating Alzheimer's disease, vascular dementia, Pick's disease, Creutzfeldt-jakob's disease, dementia caused by head injury or Parkinson's disease comprises 0.1-50 wt.% of 60-80% of methanol soluble extract of Nelumbinis Semen as an effective ingredient.

Abstract translation: 提供Nelumbinis Semen的提取物以显示改善记忆和学习能力的效果以及在小鼠的被动回避试验期间增加脑细胞增殖的效果，从而有效地用作预防和治疗认知障碍相关疾病的组合物。 用于预防和治疗阿尔茨海默氏病，血管性痴呆，皮克病，克雅氏病，由头部损伤或帕金森病引起的痴呆的药物组合物包含0.1-50重量％的60-80％的Nelumbinis Semen的可溶性甲醇提取物作为 有效成分。