公开(公告)号：KR1020050000255A

公开(公告)日：2005-01-03

申请号：KR1020030040864

申请日：2003-06-23

Applicant: 박래길

Inventor： 박래길 ,  김명선 ,  김진경

IPC: A61K36/185 ,  A61P3/04

CPC classification number: A23L33/105 ,  A23V2002/00 ,  A23V2200/332 ,  A23V2250/21

Abstract: PURPOSE: Provided is the Hibiscus sabdariffa extract which inhibits the accumulation of fatty acids and the differentiation of adipocytes by suppressing the expression of adipogenic transcription factors. CONSTITUTION: The extract of Hibiscus sabdariffa is characterized by suppressing the expression of CCAAT element binding protein(C/EBP)α and peroxisome proliferator-activated receptor(PPAR)γ. Therefore, the extract inhibits the accumulation of fatty acids and the differentiation of adipocytes by suppressing the expression of adipogenic transcription factors containing C/EBPα and PPARγ.

Abstract translation: 目的：提供通过抑制脂肪形成转录因子的表达来抑制脂肪酸的积累和脂肪细胞分化的木槿sabdariffa提取物。 构成：木槿提取物的特征在于抑制CCAAT元件结合蛋白（C / EBP）α和过氧化物酶体增殖物激活受体（PPAR）γ的表达。 因此，通过抑制含有C /EBPα和PPARγ的成脂转录因子的表达，提取物抑制脂肪酸的积累和脂肪细胞的分化。