Abstract:
PURPOSE: A Cleistocalyx operculatus-derived compounds and a composition containing the same are provided to prevent and treat diabetes. CONSTITUTION: A pharmaceutical composition for preventing or treating diabetes contains extract from Cleistocalyx operculatus using C1-C4 alcohol, a C1-C4 alcohol solution, hexane or ethyl acetate or 4,2',4'-Trihydroxy-6'-methoxy-3',5'-dimethylchalcone, 2',4'-Dihydroxy-6'-methoxy-3',5'-dimethylchalcone, 2',4'-Dihydroxy-3'-methyl-6'-methoxychalcone, or 2,2',4'-Trihydroxy-6'-methoxy-3',5'-dimethylchalcone isolated from the extract. A health functional food for preventing or treating diabetes contains the compounds.