公开(公告)号：KR1020110063621A

公开(公告)日：2011-06-13

申请号：KR1020110035147

申请日：2011-04-15

Applicant: 서울대학교산학협력단

Inventor： 조현선 ,  심지원 ,  김재범 ,  이준호

IPC: C12N9/20 ,  C12N15/55 ,  C12N15/63

Abstract: PURPOSE: A novel lipase induced by fasting and a gene encoding the same are provided to develop a therapeutic agent for obesity and to be used in foods, detergents, fine chemicals, and cosmetics. CONSTITUTION: A novel lipase induced by fasting contains an amino acid sequence of sequence number 2. A lipase gene encoding the lipase has a base sequence of sequence number 4. A recombinant vector contains the lipase gene. The lipase gene is fil-1 and fil-2 genes. The novel lipase is prepared by introducing fil-1 and fil-2 genes to wild type C. elegans and transforming an insect.

Abstract translation: 目的：提供通过禁食诱导的新型脂肪酶和编码其的基因，以开发用于肥胖症的治疗剂并用于食品，洗涤剂，精细化学品和化妆品中。 构成：通过禁食诱导的新型脂肪酶含有序列号2的氨基酸序列。编码脂肪酶的脂肪酶基因具有序列号4的碱基序列。重组载体含有脂肪酶基因。 脂肪酶基因是fil-1和fil-2基因。 通过将fil-1和fil-2基因导入野生型秀丽隐杆线虫并转化昆虫来制备新型脂肪酶。

公开(公告)号：KR1020100086390A

公开(公告)日：2010-07-30

申请号：KR1020090005749

申请日：2009-01-22

Applicant: 서울대학교산학협력단

Inventor： 조현선 ,  심지원 ,  김재범 ,  이준호

IPC: C12N9/20 ,  C12N15/63

CPC classification number: C12N9/20 ,  A23L29/06 ,  C11D3/38627

Abstract: PURPOSE: A novel lipase which is induced by fasting is provided to develop a therapeutic agent for obesity relating to lipid granule and to use in industries such as food, detergent, and cosmetics. CONSTITUTION: A novel lipase which is induced by fasting has an amino acid sequence of sequence number 1 or 2. A gene encoding the lipase of sequence number 1 has base sequence of sequence number 3. A gene encoding the lipase of sequence number 2 has base sequence number 4. A recombinant vector contains the lipase gene having sequence number 3 or 4. The recombinant vector is an expression vector.

Abstract translation: 目的：提供一种通过禁食诱导的新型脂肪酶，以开发与脂质颗粒相关的肥胖症治疗剂，并用于食品，洗涤剂和化妆品等行业。 构成：通过空腹诱导的新型脂肪酶具有序列号1或2的氨基酸序列。编码序列号1的脂肪酶的基因具有序列号3的碱基序列。编码序列号2的脂肪酶的基因具有碱基 序列号4.重组载体含有序列号3或4的脂肪酶基因。重组载体是表达载体。