公开(公告)号：KR1020100121969A

公开(公告)日：2010-11-19

申请号：KR1020090040932

申请日：2009-05-11

Applicant: 서울대학교산학협력단

Inventor： 장정식 ,  박태현 ,  윤현석 ,  이상훈 ,  권오석 ,  송현석 ,  오은해

IPC: G01N27/327 ,  G01N33/40 ,  B82B1/00

Abstract: PURPOSE: A manufacturing method of an olfactory sense nano biosensor which combines the human olfactory receptor protein and a conductivity polymer nanofiber is provided to attach the human olfactory receptor protein which applies to the receptor to the 1D conductive polymer nano material, thereby providing unlabelled FET olfactory nano bio sensor. CONSTITUTION: An electrode substrate is a surface modified to amine radical. The conductivity polymer nanomaterial having functional group uses condensation reaction and is fixed to the electrode substrate which is surface-modified. As the olfactory receptor protein uses the condensation reaction, the conductive polymer nano material having the functional group fixed to the electrode substrates is attached. An electric signal according to the chemical/electrical characteristic change between a first and a second transistor uses a FET(Field Effect Transistor) array utilizing the nano biosensor medium and is detected.

Abstract translation: 目的：提供一种结合人类嗅觉受体蛋白和导电性聚合物纳米纤维的嗅觉纳米生物传感器的制造方法，将适用于受体的人类嗅觉受体蛋白质附着到1D导电聚合物纳米材料上，从而提供未标记的FET嗅觉 纳米生物传感器。 构成：电极基底是修饰成胺基的表面。 具有官能团的导电性聚合物纳米材料使用缩合反应并固定在表面改性的电极基体上。 由于嗅觉受体蛋白使用缩合反应，所以具有固定在电极基板上的官能团的导电性聚合物纳米材料被附着。 根据第一和第二晶体管之间的化学/电特性变化的电信号使用利用纳米生物传感器介质的FET（场效应晶体管）阵列并被检测。

公开(公告)号：KR101092724B1

公开(公告)日：2011-12-09

申请号：KR1020090040932

申请日：2009-05-11

Applicant: 서울대학교산학협력단

Inventor： 장정식 ,  박태현 ,  윤현석 ,  이상훈 ,  권오석 ,  송현석 ,  오은해

IPC: G01N27/327 ,  G01N33/40 ,  B82B1/00

Abstract: 본발명에따르면, 제조된전도성고분자나노재료를전극기판상에고정시켜고분자나노재료와금속전극간의양질의전기적접촉을유지하고전극에고정된고분자나노재료에후각수용체단백질(olfactory receptor)을선택적으로고정화하여특정냄새를유발하는타겟냄새미립자와의결합을통해전도성고분자내의전하운반체(charge carrier)들의축적및 감소를유도하여전기전도도의변화로나타나효과적으로냄새미립자들을인지할수 있다. 나노사이즈의일차원적고분자는높은표면적과일방향성전기적성질로인하여, 분석물(anaylte)과의상호작용에있어서센서의향상된감도와실시간반응을제공한다는장점이있다.