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    후각 반응을 증가시키는 세포 기반 후각 센서 및 이를 이용한 후각 반응을 증가시키는 방법
    1.
    发明公开
    후각 반응을 증가시키는 세포 기반 후각 센서 및 이를 이용한 후각 반응을 증가시키는 방법 有权
    用于增加OLFACTORY反应的OLFACTORY传感器和使用该方法增加OLFACTORY反应的方法

    公开(公告)号：KR1020110008571A

    公开(公告)日：2011-01-27

    申请号：KR1020090065980

    申请日：2009-07-20

    Applicant: 서울대학교산학협력단

    Inventor： 박태현 ,  김성준 ,  이상훈 ,  정세훈 ,  전상범

    IPC: G01N27/327 ,  G01N33/497 ,  G01N27/416

    Abstract: PURPOSE: A cell-based olfactory sensor for increasing olfactory reaction and a method for increasing olfactory reaction using the same are provided to improve sensitivity on low olfactory reaction by increment in the olfactory reaction of olfactory cells. CONSTITUTION: A cell-based olfactory sensor for increasing olfactory reaction comprises an MEA(10), a wire portion(20), a chamber(30), an olfactory receptor protein expressed recombinant cell(40), a stimulation signal supplying unit(50), an output signal processing unit(60), a buffer(70), and a reference electrode(80). The wire portion is connected to the MEA. The chamber is formed in order to hold culture fluid for the cell culture on the substrate of the MEA. The cell is cultivated in the MEA within the chamber. The stimulation signal supplying unit applies sensitive signals to the cell cultivated in the MEA. The output signal processing unit outputs the variations of voltage at the cell cultivated in the MEA. The buffer is included within the chamber. The electrode is dipped in the buffer.

    Abstract translation: 目的：提供一种用于增加嗅觉反应的基于细胞的嗅觉传感器，以及使用其提高嗅觉反应的方法，以通过嗅觉细胞的嗅觉反应增加来提高对低嗅觉反应的敏感性。 构成：用于增加嗅觉反应的基于细胞的嗅觉传感器包括MEA（10），线部分（20），室（30），表达重组细胞的嗅觉受体蛋白（40），刺激信号提供单元（50） ），输出信号处理单元（60），缓冲器（70）和参考电极（80）。 电线部分连接到MEA。 形成腔室以便将细胞培养物的培养液保持在MEA的基质上。 细胞在室内的MEA中培养。 刺激信号提供单元对MEA中培养的细胞施加敏感信号。 输出信号处理单元输出在MEA中培养的细胞上的电压变化。 缓冲器包含在腔室内。 将电极浸入缓冲液中。

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