公开(公告)号：KR101099826B1

公开(公告)日：2011-12-27

申请号：KR1020090012608

申请日：2009-02-16

Applicant: 서울대학교산학협력단

Inventor： 김대덕 ,  조현종 ,  박홍매

IPC: A61K9/10 ,  A61P37/08 ,  A61K47/44

Abstract: 본발명은항알러지성약물을활성성분으로함유하며, 마이크로에멀젼또는온도감응성겔의형태로존재하는비강투여용액상제제에관한것으로, 상기비강투여용액상제제는경구투여가곤란한환자에게손쉽게투여할수 있고, 경구투여시발생할수 있는위장관에서의부작용및 전신부작용을최소화할수 있다. 또한, 전신흡수가필요한약물의경우는생체내이용율을증가시킬수 있고, 비강점막에작용하는약물의경우는약물작용점근처에직접약물을전달함으로써약리작용을최대화할수 있는장점이있다.

公开(公告)号：KR1020100093428A

公开(公告)日：2010-08-25

申请号：KR1020090012608

申请日：2009-02-16

Applicant: 서울대학교산학협력단

Inventor： 김대덕 ,  조현종 ,  박홍매

IPC: A61K9/10 ,  A61P37/08 ,  A61K47/44

CPC classification number: A61K9/0043 ,  A61K9/08 ,  A61K9/1075 ,  A61K31/445 ,  Y10S514/885

Abstract: PURPOSE: A liquid phase formulation for nasal administration containing antiallergic A drug is provided to easily administrate and to minimize side effects. CONSTITUTION: A liquid phase formulation for nasal administration contains 0.1-5 weight% of antiallergic drug, 2-10 weight% of oil, 20-70 weight aprts of% surfactant. The antiallergic drug is anti-histamin agent, steroid drug. The liquid phase formulation is microemulsion.

Abstract translation: 目的：提供含有抗过敏药物的用于鼻内给药的液相制剂以容易地施用并尽量减少副作用。 构成：用于鼻内给药的液相制剂含有0.1-5重量％的抗过敏药物，2-10重量％的油，20-70重量％的表面活性剂。 抗过敏药物是抗组胺药，类固醇药物。 液相制剂是微乳液。