公开(公告)号：KR1020120027950A

公开(公告)日：2012-03-22

申请号：KR1020100089829

申请日：2010-09-14

Applicant: 서울대학교산학협력단

Inventor： 이정훈 ,  차미선 ,  홍주희 ,  최정인

IPC: C12N13/00 ,  C12M1/42 ,  C12Q1/02

CPC classification number: C12M33/00 ,  C12M35/06

Abstract: PURPOSE: A method for teleportation of organells and a magnetic particle complex for the same are provided to selectively manipulate one organells. CONSTITUTION: A method for teleportation of organells comprises: a step of injecting bacteria magnetic particle complex into cells, in which biologically active material is conjugated; a step of binding the magnetic particle complex with the organells by specific binding between the biologically active material and organells; and a step of applying outer magnetic field to move the organells. The organells include chromosome or mitochondria.

Abstract translation: 目的：提供一种用于传送细胞器的方法和用于其的磁性颗粒复合物以选择性地操纵一个细胞器。 构成：用于传送细胞器的方法包括：将细菌磁性颗粒复合体注入生物活性材料共轭的细胞中的步骤; 通过生物活性材料和有机体之间的特异性结合将磁性颗粒复合物与有机体结合的步骤; 以及施加外部磁场以移动所述有机体的步骤。 细胞器包括染色体或线粒体。

公开(公告)号：KR101213971B1

公开(公告)日：2012-12-20

申请号：KR1020100089829

申请日：2010-09-14

Applicant: 서울대학교산학협력단

Inventor： 이정훈 ,  차미선 ,  홍주희 ,  최정인

IPC: C12N13/00 ,  C12M1/42 ,  C12Q1/02

CPC classification number: C12M33/00 ,  C12M35/06

Abstract: 세포소기관원격이동방법, 장치및 이를위한자성입자복합체가제공된다. 본발명에따른세포소기관원격이동방법은세포소기관과특이적으로결합할수 있는생물학적활성물질이결합된박테리아자성입자복합체를세포내로주입시키는단계; 상기생물학적활성물질과세포소기관의특이적결합에따라상기자성입자복합체가상기세포소기관에결합하는단계; 및외부자기장인가를인가하여상기자성입자복합체가결합된세포소기관을이동시키는단계를포함하는것을특징으로하며, 세포의이동없이크로모솜과같은세포소기관과자성복합체를특이적으로결합시킨후, 세포를고정화시킴으로써외부에인가되는자기장에의하여세포내기관만을선택적으로조작할수 있다