Abstract:
본 발명은 염증질환 예방 및 치료를 위한 오메가 3 다불포화지방산을 발현하는 이중형질전환 fat-1/무모 마우스의 제조방법 및 이의 용도에 관한 것으로, 구체적으로, 본 발명자들은 fat-1 유전자를 지니고 있는 마우스와 SKH-1 계통의 무모(hairless) 마우스의 교배를 반복하여, fat-1 유전자를 지니고 있는 마우스의 유전적 배경이 SKH-1 계통의 무모 마우스로 96.875% 필터레이션(filtration)된 마우스를 획득하였고, 상기 이중 형질전환 마우스는 오메가 3 다불포화지방산을 발현하므로, 오메가 3 다불포화지방산의 항염증 효과를 관찰하는 용도에 유용하게 사용될 수 있다.
Abstract:
An anti-Helicobacter pylori composition containing vitamin C is provided to prevent the side effects of antibiotics, the appearance of antibiotics-resistant bacteria, and reinfection in the inhibition of Helicobacter pylori. A growth inhibitor of Helicobacter pylori comprises an urease inhibitor containing vitamin C. A healthful food containing vitamin C has an urease inhibiting effect. Vitamin C is effective in inhibiting the generation of ammonia caused by the activity of urease in livestock excretions, therefore an ammonia inhibitor containing vitamin C is used as an environment improving agent.
Abstract:
PURPOSE: An inhibitor for refractory prostate cancer containing resveratrol is provided to suppress progression of prostate cancer and to enhance drug efficiency. CONSTITUTION: An inhibitor for refractory prostate cancer contains resveratrol. The inhibitor is combined with flutamide. The resveratrol is isolated from grape, mulberry, peanut, raspberry, cranberry or cuspidati Radix. The resveratrol suppresses or prevents growth of prostate cancer. The inhibitor for refractory prostate cancer is manufactured in the form of oral, parenteral or local administration.