Abstract:
본원은 비소세포폐암의 치료에 사용되는 EGFR 표적 항암치료제와 유안후아딘을 조합으로 포함하는 비소세포폐암의 상기 약물에 대한 내성을 극복, 감소 또는 지연시키는 조성물을 개시한다. 본원에 따른 조성물은 내성을 억제할 수 있어 비소세포폐암의 치료에 효과적으로 사용될 수 있다.
Abstract:
본원은 텔렉타디엄 동나이엔스( Telectadium dongnaiense ) 추출물을 유효성분으로 포함하는 대장암 예방 및 치료용 약학조성물, 및 건강기능식품에 관한 것으로, 상기 추출물은 Wnt/β-카테닌 신호전달계를 표적으로 하여 Wnt 신호전달계의 이상으로 인한 암의 치료 또는 항암 보조제로 유용하게 사용될 수 있다.
Abstract:
A skin whitening composition is provided to suppress tyrosinase activation and melanogenesis using a Physalis alkekengi var. francheti extract. A pharmaceutical composition for skin whitening comprises a Physalis alkekengi var. francheti as an active ingredient. A solvent for extracting is selected among water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butyleneglycol, propyleneglycol, hydrous butyleneglycol, hydrous propyleneglycol, and hydrous glycerin. The pharmaceutical composition is used in a form of cream, gel, patch, spray, ointment, lotion, liniment, paste, or cataplasma. A cosmetic composition is used in a form of skin, lotion, nutrition lotion, nutrition cream, massage cream, essence, or pack.
Abstract:
본 발명은 까실쑥부쟁이 (Aster ageratoides Turcz. var. ageratoides)의 추출물을 유효성분으로 함유하는 화장료 조성물에 관한 것으로, 구체적으로 시험관 내 ( in vitro ) 실험에서 우수한 티로시나제 저해활성을 나타내고, 동물세포 내 실험에서 멜라닌 합성 저해 활성을 나타내는 화장료 조성물로 유용하게 이용될 수 있다.
Abstract:
PURPOSE: A cosmetic composition containing Aster ageratoides Turcz. var. ageratoides extract is provided to suppress tyrosinase and melanogenesis. CONSTITUTION: A cosmetic composition for whitening contains Aster ageratoides Turcz. var. ageratoides extract as an active ingredient. The Aster ageratoides Turcz. var. ageratoides extract is obtained by isolating petals, branches, stems, leaves, immature fruits, fruits using water, low alcohol of 1-4 carbon atoms, propylene glycol, acetic ethyl, butylenes glycol, ether, or chloroform. The cosmetic composition contains 0.001-90 weight% of Aster ageratoides Turcz. var. ageratoides extract.
Abstract:
PURPOSE: A composition for oral administration containing Aster ageratoides Turcz. var. ageratoides extract is provided to suppress tyrosinase and melanogenesis. CONSTITUTION: A composition for oral administration with whitening effect contains Aster ageratoides Turcz. var. ageratoides extract as an active ingredient. The Aster ageratoides Turcz. var. ageratoides is isolated from petal, branch, stem, leaf, immature fruit and fruit using water, low alcohol of 1-4 carbon atoms, propylene glycol, ethyl acetate, butylenes glycol, ether or chloroform at 10-100°C for 1 hour to 4 days.
Abstract:
A food additive comprising Physalis alkekengi extract is provided to show excellent tyrosinase inhibiting activity during in vitro experiment as well as melanin synthesis-inhibiting activity using an animal cell line of Melan-A. A food additive comprises 0.1-50wt% of Physalis alkekengi extract showing a whitening effect. The Physalis alkekengi extract can be used for at least one food selected among dried fruit products, fruit juices, vegetable juices, noodles, agricultural processed foods, marine processed foods, dairy products, fermented milk foods, grain products, microorganism fermented foods, seasonings, meat processed products and the like. A method for preparing Physalis alkekengi extract comprises the following steps of: mixing Physalis alkekengi and a solvent; performing hot-water extraction, reflux extraction, immersion extraction or pressure extraction at 10-100‹C for 1-4 days; and centrifuging, vacuum-filtering, concentrating and freeze-drying the extract. The solvent is one or more materials selected from the group consisting of water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butylene glycol, propylene glycol, hydrated butylene glycol, hydrated propylene glycol and hydrated glycerin.
Abstract:
본 발명은 까실쑥부쟁이 (Aster ageratoides Turcz. var. ageratoides)의 추출물을 유효성분으로 함유하는 경구 투여용 조성물에 관한 것으로, 구체적으로 시험관 내 ( in vitro ) 실험에서 우수한 티로시나제 저해활성을 나타내고, 동물세포 내 실험에서 멜라닌 합성 저해 활성을 나타내는 식품 첨가제 및 식품으로 유용하게 이용될 수 있는 경구 투여용 조성물에 관한 것이다.
Abstract:
A skin whitening composition is provided to suppress tyrosinase activation and melanogenesis using a Physalis alkekengi var. francheti extract. A pharmaceutical composition for skin whitening comprises a Physalis alkekengi var. francheti as an active ingredient. A solvent for extracting is selected among water, ethanol, methanol, propanol, butanol, acetone, ethylacetate, hexane, butyleneglycol, propyleneglycol, hydrous butyleneglycol, hydrous propyleneglycol, and hydrous glycerin. The pharmaceutical composition is used in a form of cream, gel, patch, spray, ointment, lotion, liniment, paste, or cataplasma. A cosmetic composition is used in a form of skin, lotion, nutrition lotion, nutrition cream, massage cream, essence, or pack.