公开(公告)号：KR100841207B1

公开(公告)日：2008-06-24

申请号：KR1020070009776

申请日：2007-01-31

Applicant: 성균관대학교산학협력단

Inventor： 권무식 ,  신우석 ,  한보람

IPC: C12N15/66 ,  C12N15/63 ,  C12N15/09

CPC classification number: A61K39/102 ,  A61K2039/53 ,  A61K2039/552

Abstract: A peptide vaccine using an outer membrane protein H(OmpH) of Pasteurella multocida is provided to be used for preparing a vaccine which shows excellent activity and is applicable into the body through various pathways. A vaccine for preventing and treating porcine atrophic rhinitis comprises a total or a portion of a recombinant outer membrane protein H of a Pasteurella multocida(D:4) strain expressed from a recombinant expression vector including a gene having at least one sequence of SEQ ID : NO. 7, SEQ ID : NO. 8, SEQ ID : NO. 9, SEQ ID : NO. 10 and SEQ ID : NO. 11 encoding a total or a portion of an OmpH of the Pasteurella multocida(D:4) strain or a pharmaceutically acceptable carrier.

Abstract translation: 提供一种使用多巴斯巴斯服务的外膜蛋白H（OmpH）的肽疫苗，用于制备显示出优异活性并通过各种途径适用于人体的疫苗。 用于预防和治疗猪萎缩性鼻炎的疫苗包含由重组表达载体表达的巴斯德毕赤酵母（D：4）菌株的重组外膜蛋白H的全部或部分，所述重组表达载体包含具有至少一个SEQ ID： 没有。 7，SEQ ID NO： 8，SEQ ID NO： 9，SEQ ID NO： 10和SEQ ID NO： 11编码整个或一部分多杀巴斯德氏菌（D：4）菌株的OmpH或药学上可接受的载体。