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公开(公告)号:KR1020130081952A
公开(公告)日:2013-07-18
申请号:KR1020120003081
申请日:2012-01-10
Applicant: 삼성전자주식회사 , 아주대학교산학협력단
IPC: G01N33/574 , C12N5/095
CPC classification number: C07K14/705 , C12Q1/6881 , C12Q1/6886 , C12Q2600/158 , G01N33/57484
Abstract: PURPOSE: A biomarker for diagnosis of cancer is provided to be able to efficiently detect and isolate the cancer stem cell or the epithelial-mesenchymal transited circulating tumor cell. CONSTITUTION: A biomarker for detecting the cancer stem cell or the epithelial-mesenchymal transited circulating tumor cell includes Caveolin-1 of which the expression relatively increases in the cancer cell compared to the normal cell. A kit for detecting the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell includes Caveolin-1 or an antibody specifically binding to its fragment, or its antigen binding fragment. A method of isolating the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell comprises a step of detecting the cancer stem cell or the epithelium-mesenchymal transited circulating tumor cell in which Caveolin-1 is expressed on the cell surface from a biological sample; and a step of isolating the detected cancer stem cell or epithelium-mesnchymal transited circulating tumor cell from the biological sample. [Reference numerals] (AA) EMT derived cancer cell; (BB) Cancer cell
Abstract translation: 目的:提供诊断癌症的生物标志物,以便能够有效地检测和分离癌症干细胞或上皮 - 间质转运的循环肿瘤细胞。 构成:用于检测癌症干细胞或上皮 - 间质转运循环肿瘤细胞的生物标志物包括与正常细胞相比,癌细胞中表达相对增加的窖蛋白-1。 用于检测癌症干细胞或上皮 - 间质转运循环肿瘤细胞的试剂盒包括窖蛋白-1或与其片段特异性结合的抗体或其抗原结合片段。 分离癌症干细胞或上皮 - 间质转运循环肿瘤细胞的方法包括检测癌细胞或上皮 - 间质转运循环肿瘤细胞的步骤,其中窖蛋白-1在细胞表面上从生物样品中表达 ; 以及从生物样品中分离检测到的癌干细胞或上皮 - 细胞间充质循环肿瘤细胞的步骤。 (AA)EMT衍生的癌细胞; (BB)癌细胞
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公开(公告)号:KR101524845B1
公开(公告)日:2015-06-04
申请号:KR1020140063994
申请日:2014-05-27
Applicant: 아주대학교산학협력단
Abstract: 진공청소기에관한발명이개시된다. 본발명에따른진공청소기는: 흡입구몸체와착탈가능하게연결되는주흡입관; 주흡입관의내측에슬라이드이동가능하게삽입결합되는보조흡입관; 주흡입관의내측에회동가능하게설치되고, 주흡입관의일부를개폐하는개폐판; 및주흡입관에설치되고, 개폐판을개폐시키는개폐작동부;를포함한다.
Abstract translation: 本发明涉及真空吸尘器。 根据本发明的真空吸尘器包括:主吸收管,其连接到可吸收体上; 插入主吸收管的内侧的辅助吸收管被滑动; 一个开闭板,安装在主吸收管的内侧以便旋转,并打开和关闭主吸收管的一部分; 以及安装在主吸收管上的打开和关闭操作部分,并且打开和关闭开闭板。
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