公开(公告)号：KR101359728B1

公开(公告)日：2014-02-24

申请号：KR1020130031776

申请日：2013-03-25

Applicant: 원광대학교산학협력단

Inventor： 이영미 ,  차지윤 ,  권영배 ,  신명걸 ,  김대기 ,  이규철 ,  김대종

IPC: A61K36/47 ,  A61P29/00

CPC classification number: A61K36/47 ,  A23L33/105 ,  A23V2002/00 ,  A23V2200/324

Abstract: The present invention relates to a composition for treating or preventing inflammatory diseases containing fractions of Euphorbia humifusa Willd or Euphorbia supina Rafin as an effective component. The fractions of Euphorbia humifusa Willd or Euphorbia supina Rafin according to the present invention is confirmed to have an excellent anti-inflammatory effect in a mouse model in which ulcerative colitis is induced using DSS, is confirmed to have an excellent anti-inflammatory effect in a cell model in which the inflammation is induced using LPS in a RAW 264.7 cell, and is capable of being used for preventing and treating inflammatory diseases.

Abstract translation: 本发明涉及用于治疗或预防含有大戟属（Euphorbia humifusa Willd）或大戟属（Euphorbia supina Rafin）的部分的炎性疾病的组合物作为有效成分。 根据本发明的大戟属（Euphorbia humifusa Willd）或大戟草（Euphorbia supina Rafin）的级分被确认为在使用DSS诱导溃疡性结肠炎的小鼠模型中具有优异的抗炎作用，确认其具有优异的抗炎作用 细胞模型，其中在RAW 264.7细胞中使用LPS诱导炎症，并且能够用于预防和治疗炎性疾病。