公开(公告)号：KR1020140119933A

公开(公告)日：2014-10-13

申请号：KR1020130034505

申请日：2013-03-29

Applicant: 임실생약영농조합법인

Inventor： 강현주 ,  김현수 ,  전인화 ,  목지예 ,  정승일 ,  심재석 ,  장선일

IPC: A61K36/28 ,  A61K36/287 ,  A61P19/02

Abstract: The present invention relates to a composition for alleviating arthritis, which is effective for alleviating rheumatic arthritis symptoms by comprising Cirsium japonicum var. ussuriense leap extracts, and more specifically, to a composition for alleviating arthritis, which is highly effective in alleviating arthritis by comprising Cirsium japonicum var. ussuriense leap extracts, significantly decreasing infiltration of not only inflammatory cell but also mast cell, inhibiting cytokine which induces inflammation such as PGE2, TNF-α, IL-6, and IL-4, and increasing IL-10 which is anti-inflammatory cytokine.

Abstract translation: 本发明涉及一种用于缓解关节炎的组合物，其通过包括日本um um属（Carisium japonicum var。）来减轻风湿性关节炎症状。 尤其是用于减轻关节炎的组合物，其通过包含日本um um变种来缓解关节炎是非常有效的。 ususuriense飞跃提取物，显着减少渗透不仅炎症细胞，而且肥大细胞，抑制细胞因子诱导炎症如PGE2，TNF-α，IL-6和IL-4，并增加IL-10是抗炎细胞因子 。

公开(公告)号：KR101352591B1

公开(公告)日：2014-01-22

申请号：KR1020120029135

申请日：2012-03-22

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  목지예 ,  강현주 ,  조정근 ,  전인화 ,  김현수 ,  박지민 ,  정승일 ,  심재석

IPC: A61K36/287 ,  A61K36/28 ,  A61P7/00

Abstract: 본 발명은 엉겅퀴 추출물을 함유함으로써 적혈구의 용혈을 억제하고 혈장의 산화적 손상을 보호하며 혈관 손상을 방지하여 혈행을 개선시킴으로써 신체 질환의 예방 및 개선이 가능한 조성물에 관한 것이다.

公开(公告)号：KR101374674B1

公开(公告)日：2014-03-19

申请号：KR1020130034504

申请日：2013-03-29

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  강현주 ,  정승일 ,  김현수 ,  전인화 ,  목지예 ,  심재석

IPC: A61K36/28 ,  A61P7/06 ,  A61P7/00 ,  A61P9/00

Abstract: The present invention relates to an anti-hemolytic composition comprising more than one extract of Carpesii fructus and Farfarae flos as active ingredients, specifically to an anti-hemolytic composition which contains extracts of Carpesii fructus and Farfarae flos and controls the generation of erythrocytolysis induced by 2,2′-azobis (2-amidinopropane) dihydrochloride (AAPH) and the generation of malondialdehyde (MDA) which is a final product of a lipid oxidation material of plasma. [Reference numerals] (AA) Hemolysis rate(%); (BB) Normal control group; (CC) Negative control group; (DD) Carpesii Fructus; (EE) Farfarae Flos; (FF) Positive control group; (GG) Extract[關g/mL]

Abstract translation: 本发明涉及一种抗溶血组合物，其包含不止一种作为活性成分的枸杞提取物和Farfarae flos提取物，特别涉及含有Carpesii fructus和Farfarae flos的提取物的抗溶血组合物，并且控制由2诱导的红细胞生成 ，2'-偶氮二（2-脒基丙烷）二盐酸盐（AAPH）和产生丙二醛（MDA），其是血浆脂质氧化材料的最终产物。 （AA）溶血率（％） （BB）正常对照组; （CC）阴性对照组; （DD）Carpesii Fructus; （EE）Farfarae Flos; （FF）阳性对照组; （GG）提取物[关g / mL]

公开(公告)号：KR1020140119934A

公开(公告)日：2014-10-13

申请号：KR1020130034506

申请日：2013-03-29

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  강현주 ,  김현수 ,  전인화 ,  목지예 ,  심재석 ,  정승일

IPC: A61K36/28 ,  A61K36/287 ,  A61P9/10 ,  A61P9/00

Abstract: The present invention relates to a composition containing a thistle extract for preventing and alleviating ischemic stroke, and more specifically, to a composition for effectively alleviating symptoms of cerebral infraction by inhibiting generation of ischemic stroke such as cerebral infraction and transient ischemic attacks, alleviating the symptoms, and especially decreasing the size of cerebral infraction. The composition contains 0.5-20 wt% of the thistle extract based on the total weight of the composition.

Abstract translation: 本发明涉及含有用于预防和减轻缺血性中风的蓟提取物的组合物，更具体地，涉及通过抑制脑缺血发作和短暂性脑缺血发作等缺血性中风的产生来有效缓解脑梗死症状的组合物，减轻症状 ，特别是减少脑梗死的大小。 基于组合物的总重量，组合物含有0.5-20重量％的蓟提取物。

公开(公告)号：KR1020130107407A

公开(公告)日：2013-10-02

申请号：KR1020120029135

申请日：2012-03-22

Applicant: 임실생약영농조합법인

Inventor： 장선일 ,  목지예 ,  강현주 ,  조정근 ,  전인화 ,  김현수 ,  박지민 ,  정승일 ,  심재석

IPC: A61K36/287 ,  A61K36/28 ,  A61P7/00

Abstract: PURPOSE: A composition containing a Cirsium japonicum extract for improving blood circulation is provided to suppress hemolysis of erythrocytes, to protect oxidative damage to plasma, and to prevent blood vessel injuries, thereby improving blood circulation and preventing and treating diseases. CONSTITUTION: A composition for improving blood circulation contains 1-1000 mg/kg of a Cirsium japonicum extract. The composition is used for preventing hemolysis and oxidative damage to plasma. The composition is also used for treating thrombosis. The composition is a health food.

Abstract translation: 目的：提供含有用于改善血液循环的日本蓟马提取物的组合物，以抑制红细胞的溶血，保护血浆的氧化损伤，防止血管损伤，从而改善血液循环和预防和治疗疾病。 构成：用于改善血液循环的组合物含有1-1000mg / kg的日本蓟马提取物。 该组合物用于预防血浆溶血和氧化损伤。 该组合物也用于治疗血栓形成。 组合物是保健食品。