公开(公告)号：KR1020090041271A

公开(公告)日：2009-04-28

申请号：KR1020070106891

申请日：2007-10-23

Applicant: 재단법인서울대학교산학협력재단

Inventor： 박영환 ,  기창석 ,  나동균 ,  백현숙

IPC: A61L27/56 ,  A61L27/40 ,  A61L27/44 ,  A61L27/58 ,  A61L27/20 ,  A61L27/22 ,  A61L27/24 ,  B29C67/00

CPC classification number: A61L27/56 ,  A61L27/20 ,  A61L27/22 ,  A61L27/222 ,  A61L27/225 ,  A61L27/24 ,  A61L27/40 ,  A61L27/44 ,  A61L27/58 ,  B29C64/00

Abstract: A method for controlling the porous structure and the tissue engineering nanofiber supporter manufactured by using the same are provided, which enables the porosity which is similar to the extracellular matrix of the nature. A method for controlling the porous structure of the tissue engineering nanofiber supporter comprises: a step(S100) for preparing a mixture including the particle for the void formation and the nanofiber spreader solution; a step(S110) for preparing the nanofiber foam including the particle for the void formation using the prepared mixture; and a step(S120) for forming the nanofiber supporter in which the air gap is formed by removing the particle for the void formation of the nanofiber form.

Abstract translation: 提供了一种用于控制多孔结构的方法和使用该方法制造的组织工程纳米纤维支持体，其使得类似于自然的细胞外基质的孔隙率。 一种用于控制组织工程纳米纤维支撑体的多孔结构的方法，包括：制备包含空隙形成用颗粒和纳米纤维扩张剂溶液的混合物的步骤（S100） 制备纳米纤维泡沫的步骤（S110），其包括使用制备的混合物形成空隙的颗粒; 以及形成通过除去纳米纤维形状的空隙形成用颗粒而形成气隙的纳米纤维支持体的工序（S120）。