公开(公告)号：KR1020090088757A

公开(公告)日：2009-08-20

申请号：KR1020080014214

申请日：2008-02-15

Applicant: 재단법인서울대학교산학협력재단

Inventor： 신영기 ,  권미정 ,  오은설 ,  인용호 ,  고상석

IPC: C12Q1/68

CPC classification number: C12Q1/6837 ,  C12Q1/6851 ,  C12Q1/6876

Abstract: A method for treating and analyzing gene expression data is provided to totally analyze data in data base and identify standard expression gene. A method for selecting candidate standard expression gene comprises: a step of digitalizing the expression amount of gene in EST, SAGE and microarray data set; a step of selecting a gene which is expressed in different tissues with zero rate and expression amount of gene; In the digitalization of gene expression amount, the math equation 1 and 2 is used. The math equation 1 is EST gene expression amount = (the number of EST of specific gene in specific library/the number of total EST in specific library) X 1000000, and math equation 2 is SAGE gene expression amount = (the number of tag of specific gene in specific library / the number of total tag in specific library) X 1000000.

Abstract translation: 提供了一种治疗和分析基因表达数据的方法，以全面分析数据库中的数据并鉴定标准表达基因。 选择候选标准表达基因的方法包括：将EST，SAGE和微阵列数据集中的基因的表达量数字化的步骤; 选择在不同组织中表达的基因的步数为零，表达量为基因; 在基因表达量的数字化中，使用数学方程1和2。 数学方程式1是EST基因表达量=（特异性文库中特异性基因的EST数/特异性文库中的总EST数）×1000000，数学方程式2为SAGE基因表达量=（标记数 特定文库中的特异性基因/特定文库中的总标签数）×1000000。