公开(公告)号：KR1020090126882A

公开(公告)日：2009-12-09

申请号：KR1020080053224

申请日：2008-06-05

Applicant: 재단법인서울대학교산학협력재단

Inventor： 노동영 ,  한원식 ,  정소연

IPC: C12Q1/68

CPC classification number: G06F19/34 ,  C12Q1/6886

Abstract: PURPOSE: A method for predicting prognosis of breast cancer is provided to accurately classify patients having breast cancer into high risk group or low risk group. CONSTITUTION: A method for predicting prognosis of breast cancer comprises: a step of having information of Ki-67, bcl-2, or ER gene expression level from breast cancer cell; and a step of classifying patient into high risk group or low risk group using decision tree. In the decision tree, root node is Ki-67 gene, inner node is bcl-2 gene, ER gene and patient's age and terminal node is high risk group and low risk group.

Abstract translation: 目的：提供一种预测乳腺癌预后的方法，将乳腺癌患者准确分类为高危组或低危组。 构成：预测乳腺癌预后的方法包括：从乳腺癌细胞获得Ki-67，bcl-2或ER基因表达水平的信息的步骤; 以及使用决策树将患者分类为高风险组或低风险组的步骤。 在决策树中，根节点为Ki-67基因，内部节点为bcl-2基因，ER基因和患者年龄，终末节点为高风险组和低风险组。