公开(公告)号：KR1020090085435A

公开(公告)日：2009-08-07

申请号：KR1020080011332

申请日：2008-02-04

Applicant: 재단법인서울대학교산학협력재단

Inventor： 이진규 ,  차진명 ,  최평

IPC: B82B3/00

CPC classification number: B01J13/22 ,  A61K49/06 ,  B82Y30/00 ,  B82Y40/00

Abstract: Nanocomposite particles and a manufacturing method thereof are provided to induce fat-soluble nanoparticles on the surface of silica, thereby applying the nanocomposite particles into a living system or outside the living system. Nanocomposite particles comprise a core including fat-soluble nanoparticles and a silica shell and polyvinylpyrrolidone covering the core. The fat-soluble nanoparticles have two or more cores. The size of nanocomposite particles is 50~100 nm. The fat-soluble nanoparticles include one or more particles selected among magnetic nanoparticles and fluorescent quantum dot nanoparticles. The magnetic nanoparticles include one or more materials selected among paramagnetic materials, superparamagnetic materials and ferromagnetic metal oxide nanoparticles. The magnetic nanoparticles contain one or more oxides selected among iron, manganese, zinc, nickel, cobalt and copper oxides.

Abstract translation: 提供纳米复合物颗粒及其制造方法以在二氧化硅表面上引入脂溶性纳米颗粒，从而将纳米复合颗粒施加到生活系统或生活系统外部。 纳米复合颗粒包括包含脂溶性纳米颗粒和覆盖芯的二氧化硅壳和聚乙烯吡咯烷酮的芯。 脂溶性纳米颗粒具有两个或多个芯。 纳米复合粒子的大小为50〜100nm。 脂溶性纳米粒子包括一个或多个选自磁性纳米粒子和荧光量子点纳米粒子的粒子。 磁性纳米颗粒包括选自顺磁材料，超顺磁材料和强磁性金属氧化物纳米颗粒中的一种或多种材料。 磁性纳米颗粒含有选自铁，锰，锌，镍，钴和铜氧化物中的一种或多种氧化物。