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公开(公告)号：KR101617242B1
公开(公告)日：2016-05-03
申请号：KR1020120083406
申请日：2012-07-30
Applicant: 재단법인 제주테크노파크
Abstract: 본발명은섬오갈피근피의주요성분인아칸토산을이용한피부미백제조성물을개시한다. 본발명의피부미백제조성물에유효성분으로포함되는아칸토산은멜라노마세포인 B16F10에처리되었을때 멜라닌생성을억제하고, 멜라닌의생성에관여하는주요효소인티로시나아제, TRP-1 및 TRP-2의생성을억제할뿐만아니라, 이들단백질의발현을촉진하는전사인자인 MIFT의활성을저해한다.
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公开(公告)号：KR1020110015171A
公开(公告)日：2011-02-15
申请号：KR1020090072754
申请日：2009-08-07
Applicant: 재단법인 제주테크노파크 , (주) 인더씨 코리아
Abstract: PURPOSE: A soft coral extract is provided to ensure antioxidation, anti-inflammation, and whitening activities. CONSTITUTION: A pharmaceutical composition for antioxidation or anti-inflammation contains Alcyonium gracillimum extract or Dendronephtya gigantean extract as an active ingredient. A food composition for antioxidation contains Alcyonium gracillimum extract or Dendronephtya gigantean extract as an active ingredient. The extract is an ethyl acetate layer fraction obtained by extracting Alcyonium gracillimum or Dendronephtya gigantean with water, ethanol, or mixture solvent thereof and fractioning with water and ethyl acetate.
Abstract translation: 目的：提供柔软的珊瑚提取物，以确保抗氧化，抗炎和美白活动。 构成：用于抗氧化或抗炎的药物组合物含有青蒿素提取物或丹参龙胆提取物作为活性成分。 用于抗氧化的食物组合物含有青蒿素提取物或丹参龙胆提取物作为活性成分。 提取物是通过用水，乙醇或其混合溶剂萃取青蒿素或Dendronephtya gigantean而获得的乙酸乙酯层级分，并用水和乙酸乙酯分级。
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公开(公告)号：KR1020120127346A
公开(公告)日：2012-11-21
申请号：KR1020120083406
申请日：2012-07-30
Applicant: 재단법인 제주테크노파크
Abstract: PURPOSE: A composition for skin whitening using acanthoic acid is provided to suppress melanogenesis, TRP-1 and TRP-2 and to inhibit MIFT activation. CONSTITUTION: A cosmetic composition for skin whitening contains Acanthopanax koreanum root bark extract as an active ingredient. A soap composition for skin whitening contains the extract as an active ingredient. A pharmaceutical composition for skin whitening contains the extract as an active ingredient. The extract is a crude extract prepared by dipping Acanthopanax koreanum root bark with water, methanol, ethanol, butanol, acetone, ethyl acetate, chloroform, methylene chloride, or a mixture solvent thereof. The extract is also prepared by fractioning the crude extract with a solvent.
Abstract translation: 目的：提供使用棘皮酸进行皮肤美白的组合物，以抑制黑素生成，TRP-1和TRP-2，并抑制MIFT活化。 构成：用于皮肤美白的化妆品组合物含有刺五加根皮提取物作为活性成分。 用于皮肤美白的皂组合物含有提取物作为活性成分。 用于皮肤美白的药物组合物含有提取物作为活性成分。 提取物是通过用水，甲醇，乙醇，丁醇，丙酮，乙酸乙酯，氯仿，二氯甲烷或其混合溶剂浸渍刺五加根皮来制备的粗提物。 提取物也可以通过用溶剂对粗提物进行分级来制备。
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公开(公告)号：KR101141929B1
公开(公告)日：2012-05-09
申请号：KR1020090093918
申请日：2009-10-01
Applicant: 재단법인 제주테크노파크 , 제주특별자치도
Abstract: PURPOSE: A skin whitening composition is provided to produce a cosmetic product and soap for whitening. CONSTITUTION: A skin whitening composition contains Stichopus japonicus extract obtained by isolating Stichopus japonicus using methanol and distilled water or fraction thereof as an active ingredient. The fraction is isolated using water, distilled water, ethanol, or mixture solvent thereof. The fraction is an ethylacetate fraction of solid extract of Stichopus japonicus. The composition is a cosmetic composition or pharmaceutical composition. The pharmaceutical composition has pharmacological effects of preventing or treating melasma, fleck, or skin aging.
Abstract translation: 目的：提供皮肤增白组合物以生产美容产品和用于美白的肥皂。 组成：皮肤美白组合物含有通过使用甲醇和蒸馏水或其部分作为活性成分分离刺参得到的刺参提取物。 使用水，蒸馏水，乙醇或其混合溶剂分离馏分。 该部分是刺参（Stichopus japonicus）固体提取物的乙酸乙酯部分。 该组合物是美容组合物或药物组合物。 该药物组合物具有预防或治疗黄褐斑，斑点或皮肤老化的药理作用。
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公开(公告)号：KR1020110036321A
公开(公告)日：2011-04-07
申请号：KR1020090093918
申请日：2009-10-01
Applicant: 재단법인 제주테크노파크 , 제주특별자치도
Abstract: PURPOSE: A skin whitening composition is provided to produce a cosmetic product and soap for whitening. CONSTITUTION: A skin whitening composition contains Stichopus japonicus extract obtained by isolating Stichopus japonicus using methanol and distilled water or fraction thereof as an active ingredient. The fraction is isolated using water, distilled water, ethanol, or mixture solvent thereof. The fraction is an ethylacetate fraction of solid extract of Stichopus japonicus. The composition is a cosmetic composition or pharmaceutical composition. The pharmaceutical composition has pharmacological effects of preventing or treating melasma, fleck, or skin aging.
Abstract translation: 目的：提供皮肤美白组合物以产生美白产品和用于增白的肥皂。 构成：皮肤美白组合物含有通过使用甲醇和蒸馏水或其馏分作为活性成分分离日本extract extract得到的日本us us提取物。 使用水，蒸馏水，乙醇或其混合溶剂分离级分。 该馏分是日本油菜的固体提取物的乙酸乙酯部分。 该组合物是化妆品组合物或药物组合物。 该药物组合物具有预防或治疗黑斑病，斑点或皮肤老化的药理作用。
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Patent Agency Ranking
公开(公告)号：KR1020110137047A
公开(公告)日：2011-12-22
申请号：KR1020100057036
申请日：2010-06-16
Applicant: 재단법인 제주테크노파크
IPC: A61K36/288 , A61P29/00
Abstract: PURPOSE: A composition for anti-inflammation using Hypochoeris radicata L. extract is provided to suppress generation of NO, PGE2, and inflammatory cytokines. CONSTITUTION: A composition for anti-inflammation contains Hypochoeris radicata L. extract as an active ingredient. The extract is prepared using water, distilled water, ethanol, or mixture solvent thereof and by fractioning the solid extract into a water layer and an ethyl acetate layer. The composition is a pharmaceutical composition or food composition. A pharmaceutical composition of an iNOS inhibitor or COS-2 inhibitor contains the extract as an active ingredient.
Abstract translation: 目的：提供使用Hypochoeris radicata L.提取物的抗炎组合物，以抑制NO，PGE2和炎性细胞因子的产生。 构成：抗炎组合物含有Hypochoeris radicata L.提取物作为活性成分。 萃取液用水，蒸馏水，乙醇或其混合溶剂制备，并将固体萃取物分馏成水层和乙酸乙酯层。 组合物是药物组合物或食物组合物。 iNOS抑制剂或COS-2抑制剂的药物组合物含有提取物作为活性成分。
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公开(公告)号：KR1020110092398A
公开(公告)日：2011-08-18
申请号：KR1020100011786
申请日：2010-02-09
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K8/60 , A61K8/97 , A61K31/7048 , A61K36/254 , A61Q19/02 , C11D3/382
Abstract: PURPOSE: A skin whitening composition using acanthoic acid is provided to suppress melanogenesis and TRP-1 and TRP-2 generation. CONSTITUTION: A skin whitening composition contains 0.05-15.00 weight% of Acanthopanax Koreanum root bark extract or acanthoic acid as an active ingredient. The skin whitening composition is a cosmetic composition, soap composition, and pharmaceutical composition. The composition additionally contains a skin whitening compounds such as mercaptosuccinic acid, mercaptodextran, dihydroxy-isoquinoline or plant extract such as lemon extract, cucumber extract, mulberry extract, rosemary extract, gingko extract, or herb extract.
Abstract translation: 目的：提供使用棘皮酸的皮肤美白组合物，以抑制黑素生成和TRP-1和TRP-2的产生。 构成：皮肤美白组合物含有0.05-15.00重量％的刺五加根皮提取物或棘皮提取物作为活性成分。 皮肤美白组合物是化妆品组合物，皂组合物和药物组合物。 组合物还含有皮肤美白化合物如巯基琥珀酸，巯基葡聚糖，二羟基 - 异喹啉或植物提取物如柠檬提取物，黄瓜提取物，桑树提取物，迷迭香提取物，银杏提取物或草药提取物。
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公开(公告)号：KR1020100131808A
公开(公告)日：2010-12-16
申请号：KR1020090050592
申请日：2009-06-08
Applicant: 재단법인 제주테크노파크
CPC classification number: A61K36/03 , A23L33/105 , A61K39/39558 , A61K47/6867 , A61K2236/333
Abstract: PURPOSE: A composition for anti-cancer containing seaweed extract is provided to ensure indication of blood cancer, colon cancer, skin cancer or lung cancer and to apply to a pharmaceutical composition or food composition. CONSTITUTION: A composition for treating blood caner contains seaweed extract or fraction thereof as an active ingredient. The seaweed is Petalonia binghamiae, Sargassum nipponicum Yendo, Dictyopteris divaricata or Myelophycus simplex. The extract isolated using methanol, distilled water, ethanol, acetone, ethyl acetate, saturated normal butanol, chloroform, methylene chloride, water or mixture thereof. The seaweed fraction is obtained by removing extraction solvent from the seaweed extract to obtain solid extract, and fractioning into ethanol layer and ethylacetate layer.
Abstract translation: 目的：提供含有海藻提取物的抗癌组合物，以确保指示血癌，结肠癌，皮肤癌或肺癌，并适用于药物组合物或食物组合物。 构成：用于治疗血液的组合物含有海藻提取物或其部分作为活性成分。 海藻是花旗松属，，um o，D，属，单趾甲。 使用甲醇，蒸馏水，乙醇，丙酮，乙酸乙酯，饱和正丁醇，氯仿，二氯甲烷，水或其混合物分离提取物。 通过从海藻提取物中除去萃取溶剂获得固体提取物，并分馏成乙醇层和乙酸乙酯层，得到海藻级分。
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公开(公告)号：KR101270929B1
公开(公告)日：2013-06-03
申请号：KR1020100011786
申请日：2010-02-09
Applicant: 재단법인 제주테크노파크
Abstract: 본 발명은 섬오갈피 근피의 주요 성분인 아칸토산을 이용한 피부 미백제 조성물을 개시한다. 본 발명의 피부 미백제 조성물에 유효성분으로 포함되는 아칸토산은 멜라노마 세포인 B16F10에 처리되었을 때 멜라닌 생성을 억제하고, 멜라닌의 생성에 관여하는 주요 효소인 티로시나아제, TRP-1 및 TRP-2의 생성을 억제할 뿐만 아니라, 이들 단백질의 발현을 촉진하는 전사인자인 MIFT의 활성을 저해한다.
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公开(公告)号：KR101136742B1
公开(公告)日：2012-04-19
申请号：KR1020090072754
申请日：2009-08-07
Applicant: 재단법인 제주테크노파크 , (주) 인더씨 코리아
Abstract: PURPOSE: A soft coral extract is provided to ensure antioxidation, anti-inflammation, and whitening activities. CONSTITUTION: A pharmaceutical composition for antioxidation or anti-inflammation contains Alcyonium gracillimum extract or Dendronephtya gigantean extract as an active ingredient. A food composition for antioxidation contains Alcyonium gracillimum extract or Dendronephtya gigantean extract as an active ingredient. The extract is an ethyl acetate layer fraction obtained by extracting Alcyonium gracillimum or Dendronephtya gigantean with water, ethanol, or mixture solvent thereof and fractioning with water and ethyl acetate.
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