公开(公告)号：KR1020110035554A

公开(公告)日：2011-04-06

申请号：KR1020090093323

申请日：2009-09-30

Applicant: 전남대학교산학협력단

Inventor： 지연태 ,  강형식 ,  마상훈 ,  최고우

IPC: C12N1/00 ,  A61P35/00 ,  A61P37/04 ,  C12R1/07

Abstract: PURPOSE: A mixture strain of Bacillus sp. CMB L1 and Lactobacillus sp. CMB201 is provided to be used as a microbial formulation. CONSTITUTION: A Bacillus sp. CMB L1(KCTC 18135) and Lactobacillus sp. CMB 201(KCTC 18136) are isolated from soybean paste and have thrombolysis activity and anticancer activity. A food composition for anticancer and immunity enhancement contains the Bacillus sp. CMB L1(KCTC 18135) and Lactobacillus sp. CMB 201(KCTC 18136) or culture thereof.

Abstract translation: 目的：芽孢杆菌属混合菌株 CMB L1和乳杆菌属 提供CMB201用作微生物制剂。 构成：芽孢杆菌 CMB L1（KCTC 18135）和Lactobacillus sp。 CMB 201（KCTC 18136）与大豆酱分离，具有溶栓活性和抗癌活性。 用于抗癌和免疫增强的食物组合物包含芽孢杆菌属（Bacillus sp。 CMB L1（KCTC 18135）和Lactobacillus sp。 CMB 201（KCTC 18136）或其培养物。

公开(公告)号：KR101678859B1

公开(公告)日：2016-11-24

申请号：KR1020150101837

申请日：2015-07-17

Applicant: 전남대학교산학협력단

Inventor： 정영희 ,  윤철호 ,  김현민 ,  이가영 ,  마상훈

IPC: C07K14/415 ,  C12N15/70 ,  C12N9/02 ,  C12P23/00

Abstract: 본발명은고추유래 CaCPR1 (NADPH-cytochrome P450 reductase 1) 단백질, 상기 CaCPR1 단백질을코딩하는유전자, 상기유전자를포함하는재조합벡터, 상기재조합벡터로형질전환된숙주세포, 상기재조합벡터를숙주세포에형질전환시켜유전자를과발현시키는단계를포함하는재조합 CaCPR1 단백질을생산하는방법및 NADH를전자공여체(electron donor)로이용하여상기재조합 CaCPR1 단백질을대사체에처리하여환원된대사체를제조하는방법에관한것이다.

Abstract translation: 本发明涉及一种来源于辣椒的辣椒酸NADPH-细胞色素P450还原酶1（CaCPR1）蛋白质; 编码CaCPR1蛋白的基因; 包含该基因的重组载体; 由重组载体转化的宿主细胞; 一种重组CaCPR1蛋白的方法，其包括在宿主细胞中转化重组载体并过表达该基因的步骤; 以及通过使用NADH作为电子给体在代谢物中施用重组CaCPR1蛋白来产生还原代谢物的方法。

公开(公告)号：KR1020160010366A

公开(公告)日：2016-01-27

申请号：KR1020150101837

申请日：2015-07-17

Applicant: 전남대학교산학협력단

Inventor： 정영희 ,  윤철호 ,  김현민 ,  이가영 ,  마상훈

IPC: C07K14/415 ,  C12N15/70 ,  C12N9/02 ,  C12P23/00

Abstract: 본발명은고추유래 CaCPR1 (NADPH-cytochrome P450 reductase 1) 단백질, 상기 CaCPR1 단백질을코딩하는유전자, 상기유전자를포함하는재조합벡터, 상기재조합벡터로형질전환된숙주세포, 상기재조합벡터를숙주세포에형질전환시켜유전자를과발현시키는단계를포함하는재조합 CaCPR1 단백질을생산하는방법및 NADH를전자공여체(electron donor)로이용하여상기재조합 CaCPR1 단백질을대사체에처리하여환원된대사체를제조하는방법에관한것이다.

Abstract translation: 本发明涉及一种来源于辣椒的辣椒酸NADPH-细胞色素P450还原酶1（CaCPR1）蛋白质; 编码CaCPR1蛋白的基因; 包含该基因的重组载体; 由重组载体转化的宿主细胞; 一种重组CaCPR1蛋白的方法，其包括在宿主细胞中转化重组载体并过表达该基因的步骤; 以及通过使用NADH作为电子给体在代谢物中施用重组CaCPR1蛋白来产生还原代谢物的方法。

公开(公告)号：KR1020140035735A

公开(公告)日：2014-03-24

申请号：KR1020120102377

申请日：2012-09-14

Applicant: 전남대학교산학협력단

Inventor： 정영희 ,  마상훈

IPC: A01H5/00 ,  C12N15/82 ,  C12N15/29

CPC classification number: C12N15/8251 ,  C12N15/8205 ,  C12N15/8209 ,  C12N15/8257

Abstract: The present invention provides: a recombinant vector for targeting a target protein comprising any one base sequence among the base sequences coding four kinds of transit peptides derived from PsbP protein, a kind of oxygen evolving protein (OEC) of tobacco, to a chloroplast of a plant; plant cells transformed with the recombinant vector; a method for producing the target protein in large quantities in the chloroplast of the plant by transferring and accumulating the target protein to the chloroplast of the plant, the method comprises a step for transforming the plant cells with the recombinant vector; a method for manufacturing a transgenic plant producing the target protein in large quantities in the chloroplast, the method comprises a step for transforming the plant cells with the recombinant vector; the transgenic plant producing the target protein produced by the same method in large quantities in the chloroplast; a method for producing the target protein in large quantities in the chloroplast by transferring and accumulating the target protein from a plant tissue to the chloroplast, the method comprises a step for transiently expressing the target protein by introducing the recombinant vector into the plant tissue; and a composition for targeting the chloroplast of the plant producing the target protein comprising any one base sequence among the base sequences coding four kinds of the transit peptides.

Abstract translation: 本发明提供：用于靶向靶蛋白质的重组载体，其包含将来自PsbP蛋白质（一种烟草的放出氧气的一种OEC）的四种转运肽编码的碱基序列中的任一碱基序列， 厂; 用重组载体转化的植物细胞; 通过将靶蛋白转移并积聚到植物的叶绿体中，大量生产植物叶绿体中的靶蛋白的方法，该方法包括用重组载体转化植物细胞的步骤; 一种在叶绿体中大量生产目标蛋白质的转基因植物的制造方法，该方法包括用重组载体转化植物细胞的步骤; 通过相同的方法在叶绿体中大量生产产生靶蛋白的转基因植物; 通过将靶蛋白从植物组织转移并积聚到叶绿体中，大量生产叶绿体中的目标蛋白的方法包括通过将重组载体导入植物组织中来暂时表达靶蛋白的步骤; 以及用于靶向产生靶蛋白的植物的叶绿体的组合物，其包含编码四种转运肽的碱基序列中的任何一个碱基序列。