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公开(公告)号：KR1020090029390A
公开(公告)日：2009-03-23
申请号：KR1020070094585
申请日：2007-09-18
Applicant: 전북대학교산학협력단 , 전북대학교병원
Abstract: A manufacturing method of super paramagnetism iron oxide nanoparticle in which PVLA is coated is provided to prevent instability and agglomeration due to hydrophobicity attraction between super paramagnetism iron oxide nanoparticles and to have emulsifier functions. A manufacturing method of super paramagnetism iron oxide nanoparticle in which PVLA is coated comprises steps of: adding basic solution in ferric chloride aqueous solution and precipitating iron oxide nanoparticle; oxidizing and dialyzing he precipitated ferric oxide nano particle and manufacturing a storage solution; and mixing the PVLA solution into the storage solution and coating it. The iron chloride aqueous solution is mixed solution of the ferric chloride(II)(FeCl2) hydrate and ferric chloride(III) (FeCl3) hydrate. The basic solution is NaOH, potassium hydroxide or ammonia aqueous solution.
Abstract translation: 提供其中涂覆有PVLA的超顺磁性氧化铁纳米颗粒的制造方法，以防止由于超顺磁性氧化铁纳米粒子之间的疏水性吸引引起的不稳定性和凝聚性，并具有乳化剂功能。 PVLA涂层的超顺磁性氧化铁纳米颗粒的制造方法包括以下步骤：在氯化铁水溶液中加入碱性溶液并沉淀氧化铁纳米颗粒; 氧化和透析他沉淀氧化亚铁纳米颗粒并制造储存溶液; 并将PVLA溶液混合到储存溶液中并进行涂布。 氯化铁水溶液是氯化铁（II）（FeCl 2）水合物和氯化铁（III）（FeCl 3）水合物的混合溶液。 碱性溶液是NaOH，氢氧化钾或氨水溶液。
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公开(公告)号：KR100974083B1
公开(公告)日：2010-08-04
申请号：KR1020070094585
申请日：2007-09-18
Applicant: 전북대학교산학협력단 , 전북대학교병원
Abstract: 본 발명은 PVLA가 코팅된 초상자성 산화철 나노입자, 이의 제조방법 및 이를 포함하는 간질환 진단용 조영제에 관한 것으로, 본 발명의 PVLA가 코팅된 초상자성 산화철 나노입자는 초상자성 산화철 용액(ferrofluid)의 안정성을 확보하고 간에 선택적으로 전달됨으로써 정확하게 간질환을 진단하는 안정한 조영제로서 유용하게 사용될 수 있다.
조영제, 초상자성, 산화철 나노입자
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