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公开(公告)号：KR1020040074264A
公开(公告)日：2004-08-25
申请号：KR1020030009787
申请日：2003-02-17
Applicant: 주식회사 인트론바이오테크놀로지
IPC: C12N15/33
Abstract: PURPOSE: A nucleocapsid gene of infectious bronchitis virus is provided, which gene is useful as a molecular marker for determining and classifying the type of infectious bronchitis virus. CONSTITUTION: The nucleocapsid gene of infectious bronchitis virus has the nucleotide sequence set forth in SEQ ID NO:1, wherein the nucleocapsid gene is selected from the nucleotide sequences set forth in SEQ ID NO:2 to SEQ ID NO:39. The method for determining the type of infectious bronchitis virus comprises the steps of: (1) PCR amplifying a testing DNA using primers having the nucleotide sequences set forth in SEQ ID NO:40 and SEQ ID NO:41; (2) sequencing the PCR amplified product; and (3) comparing the sequenced nucleotide sequence with the nucleocapsid gene of SEQ ID NO:1.
Abstract translation: 目的：提供感染性支气管炎病毒的核衣壳基因，该基因可用作确定和分类感染性支气管炎病毒类型的分子标记物。 构成：感染性支气管炎病毒的核衣壳基因具有SEQ ID NO：1所示的核苷酸序列，其中核衣壳基因选自SEQ ID NO：2〜SEQ ID NO：39所示的核苷酸序列。 用于确定感染性支气管炎病毒类型的方法包括以下步骤：（1）使用具有SEQ ID NO：40和SEQ ID NO：41所示核苷酸序列的引物PCR扩增测试DNA; （2）对PCR扩增产物进行测序; 和（3）将测序的核苷酸序列与SEQ ID NO：1的核衣壳基因进行比较。
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公开(公告)号：KR100454870B1
公开(公告)日：2004-11-03
申请号：KR1020010045863
申请日：2001-07-30
Applicant: 주식회사 인트론바이오테크놀로지
IPC: C07K14/125
Abstract: PURPOSE: F(fusion) protein and HN(haemagglutinin-neuraminidase) protein of Newcastle disease virus strains and genes thereof are provided which are used as marker molecules for diagnosing newcastle disease virus and for development of a vaccine therefor. CONSTITUTION: The F protein consists of amino acids represented by one of SEQ ID NOs:14 to 26. F protein gene consists of nucleotide sequence represented by one of SEQ ID NOs: 1-13. The HN protein consists of amino acids represented by one of SEQ ID NOs:34 to 40. HN protein gene consists of nucleotide sequence represented by one of SEQ ID NOs: 27-33.
Abstract translation: 目的：提供新城疫病毒株的F（融合）蛋白质和HN（血细胞凝集素 - 神经氨酸酶）蛋白质及其基因，其用作诊断新城疫病毒的标志物分子并用于开发其疫苗。 构成：F蛋白由SEQ ID NO：14至26中的一个表示的氨基酸组成.F蛋白基因由SEQ ID NO：1-13之一表示的核苷酸序列组成。 HN蛋白由SEQ ID NO：34至40之一表示的氨基酸组成.HN蛋白基因由SEQ ID NO：27-33之一所示的核苷酸序列组成。
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公开(公告)号：KR100504763B1
公开(公告)日：2005-08-01
申请号：KR1020030009787
申请日：2003-02-17
Applicant: 주식회사 인트론바이오테크놀로지
IPC: C12N15/33
Abstract: 본 발명은
서열번호 1 로 기재되는 전염성 기관지염 바이러스(Infectious bronchitis virus)의 뉴클레오캡시드(Nucleocapsid) 유전자에 관한 것으로서, 보다 상세하게는
서열번호 2 내지
서열번호 39 로 기재되는 염기서열을 갖는 전염성 기관지염 바이러스의 뉴클레오캡시드 유전자 및 상기 유전자를 이용하여 전염성 기관지염 바이러스의 타입을 결정하는 방법에 관한 것이다. 본 발명의 뉴클레오캡시드 유전자는 전염성 기관지염 바이러스의 타입 결정 및 분류를 위한 분자 마커로 유용하게 사용될 수 있다.-
公开(公告)号：KR1020030012023A
公开(公告)日：2003-02-12
申请号：KR1020010045863
申请日：2001-07-30
Applicant: 주식회사 인트론바이오테크놀로지
IPC: C07K14/125
CPC classification number: C07K14/005 , C12N15/62 , G01N33/56983 , G01N33/68 , G01N2333/125
Abstract: PURPOSE: F(fusion) protein and HN(haemagglutinin-neuraminidase) protein of Newcastle disease virus strains and genes thereof are provided which are used as marker molecules for diagnosing newcastle disease virus and for development of a vaccine therefor. CONSTITUTION: The F protein consists of amino acids represented by one of SEQ ID NOs:14 to 26. F protein gene consists of nucleotide sequence represented by one of SEQ ID NOs: 1-13. The HN protein consists of amino acids represented by one of SEQ ID NOs:34 to 40. HN protein gene consists of nucleotide sequence represented by one of SEQ ID NOs: 27-33.
Abstract translation: 目的：提供新城疫病毒株的F（融合）蛋白和HN（血凝素 - 神经氨酸酶）蛋白及其基因，其用作诊断新城疫病毒和用于开发疫苗的标记分子。 构成：F蛋白由SEQ ID NO：14〜26之一表示的氨基酸组成.F蛋白基因由SEQ ID NO：1-13之一表示的核苷酸序列组成。 HN蛋白由SEQ ID NO：34至40之一表示的氨基酸组成.HH蛋白基因由SEQ ID NO：27-33之一表示的核苷酸序列组成。
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Patent Agency Ranking
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7.发明授权뉴캐슬병 바이러스 검출용 프라이머 및 상기 프라이머를이용한 뉴캐슬병 바이러스 검출, 병원성 및 유전형 조사방법 有权뉴캐슬병바이러스검출용프라이머및상기프라이머를이용한뉴캐슬병바이러스검출，병원성및유전형조사방뉴캐슬병
公开(公告)号：KR100437888B1
公开(公告)日：2004-07-03
申请号：KR1020010045862
申请日：2001-07-30
Applicant: 주식회사 인트론바이오테크놀로지
IPC: C12Q1/68
Abstract: PURPOSE: Provided are primers for detection of newcastle disease virus, and methods for diagnosing the newcastle disease by simultaneously performing detection and pathotyping thereof and for genotyping of the newcastle disease virus by RFLP(restriction fragment length polymorphism). CONSTITUTION: The primers for detection of newcastle disease virus are characteristically represented by the SEQ ID NO:1 and 2. The primers for pathotyping of the newcastle disease virus are characteristically represented by the SEQ ID NO:3 and 4. The method for genotyping of the newcastle disease virus is characterized by RFLP using Hinf I and Pst I as restriction enzymes, and PCR products using the primers of SEQ ID NO:1 and 2.
Abstract translation: 目的：提供了用于检测新城疫病毒的引物，以及通过同时检测和分型以及用RFLP（限制性片段长度多态性）对新城疫病毒进行基因分型来诊断新城疫的方法。 构成：用于检测新城疫病毒的引物的特征在于SEQ ID NO：1和2.用于新城疫病毒的pathotyping的引物的特征在于SEQ ID NO：3和4.用于基因分型的方法 新城疫病毒的特征在于使用Hinf I和Pst I作为限制性酶的RFLP，以及使用SEQ ID NO：1和2的引物的PCR产物。
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公开(公告)号：KR102071283B1
公开(公告)日：2020-01-30
申请号：KR1020180035533
申请日：2018-03-28
Applicant: 주식회사 인트론바이오테크놀로지
IPC: G01N33/558 , G01N33/68 , B01L3/00
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公开(公告)号：KR1020180127561A
公开(公告)日：2018-11-29
申请号：KR1020170061333
申请日：2017-05-18
Applicant: 서울대학교산학협력단 , 주식회사 인트론바이오테크놀로지
Abstract: 본발명은신규돼지 TLR2 표적펩타이드및 그동정방법에관한것으로, 더욱상세하게는 TLR2와높은친화력으로결합하는표적펩타이드인 NAGHLSQ 및그 동정방법을제공하는뛰어난효과가있다.
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公开(公告)号：KR3007281320000S
公开(公告)日：2014-02-10
申请号：KR3020120042806
申请日：2012-09-06
Applicant: 주식회사 인트론바이오테크놀로지
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