公开(公告)号：KR100962334B1

公开(公告)日：2010-06-10

申请号：KR1020090099238

申请日：2009-10-19

Applicant: 주식회사 중앙백신연구소 ,  조선대학교산학협력단

Inventor： 김은희 ,  유성식 ,  원호근 ,  오원근 ,  박준수 ,  강후원 ,  누엔티녹안

IPC: A61K36/9066 ,  A61P31/16 ,  A23L1/30 ,  A61K31/12

CPC classification number: A61K31/12 ,  A23L33/105 ,  A23V2002/00 ,  A61K36/9066 ,  A23V2250/21

Abstract: PURPOSE: A composition containing diaryheptanoid compounds for preventing and treating avian and swine influenza and novel swine-origin influenza A is provided to non-selectively suppress neuraminidase. CONSTITUTION: A pharmaceutical composition for preventing or treating oseltamivir phosphate-resistant novel swine-origin influenza A contains Curcuma longa extract as an active ingredient. The Curcuma longa extract contains bisdemethoxycurcumin, demethoxycurcumin, or curcumine. The Curcuma longa extract is obtained using ethanol, methanol, acetone, ethyl acetate, or chloroform. A health food for preventing or treating Tamiflu resistant novel swine-origin influenza A contains bisdemethoxycurcumin, demethoxycurcumin, or curcumine.

Abstract translation: 目的：提供一种含有用于预防和治疗禽流感和猪流感病毒的日化类固醇化合物和新型猪源甲型流感病毒的组合物，用于非选择性抑制神经氨酸酶。 构成：用于预防或治疗磷酸奥司他韦的新型猪源甲型流感A的药物组合物含有姜黄提取物作为活性成分。 姜黄提取物含有二去甲氧基姜黄素，去甲氧基姜黄素或姜黄素。 使用乙醇，甲醇，丙酮，乙酸乙酯或氯仿得到姜黄提取物。 用于预防或治疗Tamiflu抗性的猪源甲型流感A的保健食品含有双二甲氧基姜黄素，去甲氧基姜黄素或姜黄素。

公开(公告)号：KR101132174B1

公开(公告)日：2012-04-05

申请号：KR1020100013217

申请日：2010-02-12

Applicant: 조선대학교산학협력단

Inventor： 오원근 ,  누엔피헝 ,  누엔티녹안 ,  강후원

IPC: A61K31/343 ,  A61K31/34 ,  A61K36/25 ,  A61P3/04

Abstract: PURPOSE: A compound which activates Erythrina abyssinica-derived AMPK is provided to prevent and treat diabetes, obesity, or metabolic syndrome with less cytotoxicity. CONSTITUTION: An Erythrina abyssinica extract for preventing or treating obesity or metabolic syndrome contains erythribyssin F, erythribyssin N, erythribyssin O, sigmoidin K, isosojagol, eryvarin, or erypoegin F. A health food or pharmaceutical composition for preventing or treating obesity or metabolic syndrome contains the Erythrina abyssinica extract as an active ingredient. The pharmaceutical composition also contains pharmaceutically acceptable carrier or excipient.

公开(公告)号：KR1020110093279A

公开(公告)日：2011-08-18

申请号：KR1020100013217

申请日：2010-02-12

Applicant: 조선대학교산학협력단

Inventor： 오원근 ,  누엔피헝 ,  누엔티녹안 ,  강후원

IPC: A61K31/343 ,  A61K31/34 ,  A61K36/25 ,  A61P3/04

Abstract: PURPOSE: A compound which activates Erythrina abyssinica-derived AMPK is provided to prevent and treat diabetes, obesity, or metabolic syndrome with less cytotoxicity. CONSTITUTION: An Erythrina abyssinica extract for preventing or treating obesity or metabolic syndrome contains erythribyssin F, erythribyssin N, erythribyssin O, sigmoidin K, isosojagol, eryvarin, or erypoegin F. A health food or pharmaceutical composition for preventing or treating obesity or metabolic syndrome contains the Erythrina abyssinica extract as an active ingredient. The pharmaceutical composition also contains pharmaceutically acceptable carrier or excipient.

Abstract translation: 目的：提供一种激活源自艾氏黑质素的AMPK的化合物，以预防和治疗糖尿病，肥胖或代谢综合征，细胞毒性较小。 构成：用于预防或治疗肥胖症或代谢综合征的黑曜石提取物含有赤藓红F，红细菌素N，赤藓糖苷O，乙状结肠素K，异山梨醇，赤藓红或紫杉醇F.用于预防或治疗肥胖或代谢综合症的保健食品或药物组合物含有 白芷提取物作为活性成分。 药物组合物还含有药学上可接受的载体或赋形剂。