초상자성 산화철 나노입자를 포함하는 색전제 및 그 제조 방법
    1.
    发明公开
    초상자성 산화철 나노입자를 포함하는 색전제 및 그 제조 방법 有权
    包含超级氧化铁氧化物纳米微粒(SPIOS)的微波胶囊及其制备方法

    公开(公告)号:KR1020110035136A

    公开(公告)日:2011-04-06

    申请号:KR1020090092714

    申请日:2009-09-29

    Abstract: PURPOSE: A method for preparing an agent for embolus containing superparamagnetic iron oxide nanoparticles(SPIOs) is provided to trace particle position and state in the body. CONSTITUTION: An agent for embolus contains a spherical particle containing superparamagnetic iron oxide nanoparticles. The nanoparticle is loaded on a biocompatible polymer. The biocompatible polymer is chitosan. A method for preparing the agent for embolus comprises: a step of mixing a biocompatible polymer solution and superparamagnetic iron oxide nanoparticles; and a step of dropping the solution to a mixture solvent to form a spherical particle.

    Abstract translation: 目的:提供一种用于制备含有超顺磁性氧化铁纳米颗粒(SPIO)的栓塞剂的方法,以追踪体内的颗粒位置和状态。 构成:栓剂包含含有超顺磁性氧化铁纳米粒子的球形颗粒。 将纳米颗粒装载在生物相容的聚合物上。 生物相容性聚合物是壳聚糖。 制备栓塞剂的方法包括:混合生物相容性聚合物溶液和超顺磁性氧化铁纳米粒子的步骤; 以及将溶液滴加到混合溶剂中以形成球形颗粒的步骤。

    초상자성 산화철 나노입자 탑재 고분자 미세구의 제조 방법
    2.
    发明公开
    초상자성 산화철 나노입자 탑재 고분자 미세구의 제조 방법 有权
    超级纳米氧化物纳米颗粒(SPIOS)加载聚合物微球的制备方法

    公开(公告)号:KR1020110035134A

    公开(公告)日:2011-04-06

    申请号:KR1020090092712

    申请日:2009-09-29

    CPC classification number: B01J13/08 A61K49/06 B82Y5/00

    Abstract: PURPOSE: A producing method of hydrophilic polymeric microsphere mounting super-paramagnetic iron oxide nanoparticles is provided to uniformly disperse the super-paramagnetic iron oxide nanoparticles in the microsphere. CONSTITUTION: A producing method of hydrophilic polymeric microsphere mounting super-paramagnetic iron oxide nanoparticles comprises the following steps: mixing a bio-compatible macromolecular solution and the super-paramagnetic iron oxide nanoparticles; and dropping the mixed solution on a mixed solvent of an organic solvent layer and a coacervation medium layer, for forming the microsphere. The mounting efficiency of the super-paramagnetic iron oxide nanoparticles is greater than 90%.

    Abstract translation: 目的:提供亲水性聚合物微球安装超顺磁性氧化铁纳米颗粒的制备方法,以将超顺磁性氧化铁纳米颗粒均匀分散在微球中。 构成:亲水性聚合物微球安装超顺磁性氧化铁纳米粒子的制备方法包括以下步骤:将生物相容性大分子溶液与超顺磁性氧化铁纳米粒子混合; 并将混合溶液滴在有机溶剂层和凝聚介质层的混合溶剂上,形成微球。 超顺磁性氧化铁纳米粒子的安装效率大于90%。

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