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公开(公告)号：KR1020140070794A
公开(公告)日：2014-06-11
申请号：KR1020120135496
申请日：2012-11-27
Applicant: 차의과학대학교 산학협력단
Abstract: The present invention provides a pharmaceutical composition to improve or treat muscle atrophy disease comprising stem cells derived from umbilical cord as an active ingredient. Upon administering the stem cells derived from umbilical cord of the present invention into muscles, the administered stem cells increase the muscle cells in stem cell administered areas and increase muscle fiber size and myotility, thus the stem cells derived from umbilical cord can be effective to improve or treat muscle atrophy disease. The stem cells derived from the umbilical cord of the present invention are cultivated in a medium including an umbilical cord extract as a replacement, thereby being safely applicable clinically without concerns of safety problems such as cross-species contamination according to use of fetal bovine serum and the like.
Abstract translation: 本发明提供一种改善或治疗肌肉萎缩性疾病的药物组合物，其包含源自脐带的干细胞作为活性成分。 将本发明的源自脐带的干细胞施用于肌肉后，所施用的干细胞增加干细胞给药区域中的肌肉细胞，增加肌肉纤维的大小和肌力，因此源于脐带的干细胞可有效地改善 或治疗肌肉萎缩症。 将源自本发明的脐带的干细胞在包括脐带提取物的培养基中培养为替代物，从而临床安全应用，而不考虑安全问题，例如根据胎牛血清的使用的物种间污染， 类似。
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2.发明公开
公开(公告)号：KR1020160137864A
公开(公告)日：2016-12-01
申请号：KR1020150072125
申请日：2015-05-22
Applicant: 차의과학대학교 산학협력단
Abstract: 본발명은포유동물탯줄유래줄기세포의배양액을유효성분으로포함하는근위축증의예방또는치료용약제학적조성물을제공한다. 본발명의탯줄유래줄기세포배양액을근육내에투여하는경우, 투여된줄기세포는투여된부위의근육세포를증식시키고, 근육양을증가시키며, 근육의피로를빠르게회복시킴으로써근위축증의예방또는치료에유효하다. 본발명은줄기세포배양액을이용하기때문에줄기세포를이용한치료법의기술적, 현실적제한성을극복할수 있고상대적으로확보가용이하다는장점이있어근위축증의예방및 치료에매우효과적으로이용될수 있다.
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公开(公告)号：KR101468123B1
公开(公告)日：2014-12-08
申请号：KR1020120135496
申请日：2012-11-27
Applicant: 차의과학대학교 산학협력단
Abstract: 본발명은포유동물탯줄유래줄기세포를유효성분으로포함하는근위축질환개선또는치료용약제학적조성물을제공한다. 본발명의탯줄유래줄기세포를근육내에투여하는경우, 투여된줄기세포는투여된부위의근육세포를증식시키고, 근섬유크기및 근수축력을증가시킴으로써근위축질환의개선또는치료에유효하다. 본발명의탯줄유래줄기세포는혈청대체물로서탯줄추출물을포함하는배지에서배양하므로우태아혈청사용에따른종간오염등의안전성문제에대한우려없이안전하게임상적용이가능하다.
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