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公开(公告)号:KR1019880002522B1
公开(公告)日:1988-11-28
申请号:KR1019840008402
申请日:1984-12-27
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
IPC: A61K7/16
Abstract: Toothpastes and mouthwashes that inhibit plaque formation and gangivitis contain an orally acceptable vehicle, a polyvinylphosphonic acid (I) or its orally acceptable salts. with mol. wt. 6000-100,000. Compns. contg. 0.01-10 wt.% (I) are formulated as mouthwashes contg. an aq. alcoholic vehicle and as toothpaste contg. gelling and polishing agents, pref. with pH 4.5-9. A fluoride-contg. cpds., fragrance, and sweetener can be added to the formulations. (I) inhibits attachment of actinomyces viscosus to the teeth.
Abstract translation: 抑制斑块形成和牙龈炎的牙膏和漱口剂含有口服可接受的载体,聚乙烯基膦酸(I)或其口服可接受的盐。 与mol。 重量。 6000-100,000。 Compns。 contg。 0.01-10重量%(I)配制成漱口剂, 一个水 酒精车和牙膏。 胶凝和抛光剂,优先。 pH 4.5-9。 氟化物 香料和甜味剂可加入制剂中。 (I)抑制粘液菌粘附到牙齿上。
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公开(公告)号:KR1019880001404B1
公开(公告)日:1988-08-01
申请号:KR1019810005241
申请日:1981-12-30
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
Abstract: Water-soluble copolymer (I) comprises (1) units having the molecular configuration of units derived from vinylphosphoric acid (II); and (2) units derived from vinylphosphonyl fluoride (III). The ratio of (1) to (2) units is 2:1-25:1. Copolymers (I) are non-antibacterial agents for promoting oral hygiene as they are useful for treating, controlling or inhibiting gingivitis, which is characterised by inflammation, bleeding, recession and/or swelling of the gums and leads to periodontitis. The (I) interferes with, or inhibits, attachment of Actinomyces viscosus to tooth surfaces with redn. in placque. The (I) is pref. included in rinses and mouthwashes at 0.5- 5% concn. in aq. alcohol at pH 4.5-9 and esp. with a gelling agent.
Abstract translation: 水溶性共聚物(I)包含(1)具有衍生自乙烯基磷酸(II)的单元的分子构型的单元; 和(2)衍生自乙烯基膦酰氟(III)的单元。 (1)至(2)单位的比例为2:1-25:1。 共聚物(I)是用于促进口腔卫生的非抗菌剂,因为它们可用于治疗,控制或抑制牙龈炎,其特征在于牙龈的炎症,出血,衰退和/或肿胀并导致牙周炎。 (I)干扰或抑制粘性放线菌粘附到牙齿表面。 在placque。 (I)是pref。 包括在0.5-5%浓度的漱口水和漱口水中。 在一个水平 pH 4.5-9的酒精, 与胶凝剂。
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公开(公告)号:KR100027623B1
公开(公告)日:1989-03-13
申请号:KR1019850004549
申请日:1985-06-26
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
IPC: A61K33/42
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公开(公告)号:KR1019880002266B1
公开(公告)日:1988-10-21
申请号:KR1019850004549
申请日:1985-06-26
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
IPC: A61K33/42
CPC classification number: A61K33/42
Abstract: A method for preparing an anti-tumor agent is consists of a compn. contg. 20 parts cellulose acetate phthalate, 30 parts carnauba wax, 10 parts stearic acid, 450 parts 96%-EtOH, and 390 parts acetone which has an inhibitory effect against bone marrow.
Abstract translation: 制备抗肿瘤剂的方法由化合物 contg。 20份邻苯二甲酸乙酸纤维素,30份巴西棕榈蜡,10份硬脂酸,450份96%-EtOH和390份丙酮,对骨髓具有抑制作用。
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公开(公告)号:KR100027654B1
公开(公告)日:1989-03-16
申请号:KR1019840008402
申请日:1984-12-27
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
IPC: A61K7/16
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公开(公告)号:KR100026551B1
公开(公告)日:1988-11-15
申请号:KR1019810005241
申请日:1981-12-30
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
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公开(公告)号:KR1019880001750B1
公开(公告)日:1988-09-12
申请号:KR1019810005204
申请日:1981-12-29
Applicant: 콜게이트-파아므올리브캄파니
Inventor: 압둘개파
Abstract: The oral dentifrice toothpaste or mouth wash compsn. comprises a vehicle, at leat one cationic nitrogen-contg. antibacterial antiplaque agent whose use has been shown to stain dental sufaces and a stain-inhibiting amt. of a copolymer (I). Cpd. (I) consists of (A) n units having formula -C-HN-CH(COOH)-CH2CH2(O)-, (B) m units having formula -C-HN-CH(CH3)-(O)- and (C) P units having formula (II). The ratio (n+m): p is 5:1 to 9.5:1 and the ratio m:n is 0:1 to 0.6:1, (I) has mol. wt. 5000-150000. Pref. the antibacterial antiplaque agent is a substd. guanidine esp. chlorohexidine or alexidine.
Abstract translation: 口腔洁牙膏牙膏或口腔清洁剂。 包括载体,在一个阳离子氮气保护下。 抗菌抗菌剂的用途已被证明可以染色牙齿表面和染色抑制剂。 的共聚物(I)。 CPD。 (I)由(A)具有式-C-HN-CH(COOH)-CH 2 CH 2(O) - ,(B)m的具有式-C-HN-CH(CH 3) - (O) - 的单元的n个单元组成, (C)具有式(II)的P单元。 比率(n + m):p为5:1〜9.5:1,m:n为0:1〜0.6:1,(I)为摩尔。 重量。 5000〜150000。 县。 抗菌抗斑剂是一个细菌。 guanidine esp 氯己定或吖啶啶。
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