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公开(公告)号：KR1020150018224A
公开(公告)日：2015-02-23
申请号：KR1020130094865
申请日：2013-08-09
Applicant: 한국과학기술연구원
CPC classification number: G01N33/554 , C07K2319/20 , C07K2319/21 , C12N7/00 , C12N15/1037 , C12N2795/10222 , C12N2795/10231 , C12N2810/50 , C12N2810/859 , G01N33/588 , C12N15/11 , C12Q1/6883 , G01N33/53 , G01N33/68
Abstract: The present invention relates to a target-specific probe containing T7 bacteriophage and a targeting antibody; and a detection method, a quantitative method, or a detection kit for a biomarker using the probe. The present invention is used for a phage display in which various functional heterologous proteins and peptides are expressed on the bacteriophage surface by manipulating T7 bacteriophage using gene recombinant technology, a technique for targeting a biomarker or bacteria through an antigen-antibody specific reaction, and a method for quantitatively analyzing a target material using a quantum dot.
Abstract translation: 本发明涉及含有T7噬菌体和靶向抗体的靶特异性探针; 以及使用该探针的生物标志物的检测方法，定量方法或检测试剂盒。 本发明用于噬菌体展示，其中通过使用基因重组技术操纵T7噬菌体，通过抗原 - 抗体特异性反应靶向生物标志物或细菌的技术，在噬菌体表面上表达各种功能性异源蛋白质和肽，以及 使用量子点定量分析目标材料的方法。
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公开(公告)号：KR101551925B1
公开(公告)日：2015-09-18
申请号：KR1020130094865
申请日：2013-08-09
Applicant: 한국과학기술연구원
CPC classification number: G01N33/554 , C07K2319/20 , C07K2319/21 , C12N7/00 , C12N15/1037 , C12N2795/10222 , C12N2795/10231 , C12N2810/50 , C12N2810/859 , G01N33/588
Abstract: 본발명은 T7 박테리오파지와표적화항체를함유하는표적-특이적프로브및 상기프로브를이용한바이오마커의탐지방법, 정량방법또는탐지키트에관한것으로서, T7 박테리오파지를유전자재조합기술을이용하여다양한기능성이종단백질과펩타이드를박테리오파지표면에발현하는파지디스플레이, 항원-항체특이반응으로바이오마커나박테리아를표적화하는기술및 양자점을사용하여표적물질을정량적으로분석하는방법으로이용된다.
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