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    신규의사우루릭산및그제조방법과이를포함하는세포접착저해활성을가지는조성물
    2.
    发明授权
    신규의사우루릭산및그제조방법과이를포함하는세포접착저해활성을가지는조성물 失效
    新鲜的酸性和制备方法

    公开(公告)号：KR100252195B1

    公开(公告)日：2000-05-01

    申请号：KR1019970070614

    申请日：1997-12-19

    Applicant: 한국과학기술연구원

    Inventor： 고영희 ,  전효곤 ,  정명철 ,  이호재 ,  정영철 ,  정동호

    IPC: C07D307/36 ,  A61K31/34

    Abstract: PURPOSE: Provided is a novel saururic acid represented by the formula (I): GIMSIVKDVAK-X-AAKEAAKGALSTLSCKLAKTC, inhibiting the adhesion of cancer cell to laminin, a kind of extracellular matrix. The saururic acid is separated and purified from the roots of Caururus chinensis Baill. The novel saururic acid can be used for the prevention and treatment of cancer metastasis and inflammation resulted from cell adhesion. Also, its preparation method and a composition comprising the same are also provided. CONSTITUTION: A preparation method of saururic acid from the roots of Caururus chinensis Baill is composed of the following steps of: (a) extracting the roots of Caururus chinensis Baill with organic solvent; and (b) concentrating and purifying the produced extract solution.

    Abstract translation: 目的：提供由式（I）：GIMSIVKDVAK-X-AAKEAAKGALSTLSCKLAKTC表示的新颖的葫芦酸，抑制癌细胞对层粘连蛋白的粘附，层粘连蛋白是一种细胞外基质。 从中华百科的根中分离和纯化了sa ic酸。 这种新型的苏打酸可用于预防和治疗由癌细胞粘附引起的癌症转移和炎症。 此外，还提供了其制备方法和包含其的组合物。 构成：从中华白龙蒿根中制备的sa ic酸的制备方法为：（a）用有机溶剂提取中华白the根; 和（b）浓缩和纯化生产的提取物溶液。

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