公开(公告)号：KR101281101B1

公开(公告)日：2013-07-02

申请号：KR1020100134684

申请日：2010-12-24

Applicant: 한국과학기술연구원

Inventor： 에릭플러리 ,  김동익 ,  사트얌스와스 ,  서브하시스신하 ,  홍성민

IPC: C21D8/02 ,  C22C38/16

Abstract: 연성 및 기계적 강도가 우수한 구리 함유 오스테나이트계 스테인리스 강판 및 그 제조 방법을 제공한다. 구리 함유 오스테나이트계 스테인리스 강판의 제조 방법은, i) 1wt% 내지 5wt%의 구리를 포함하는 스테인리스 강판을 제공하는 제1 단계, ii) 강판을 냉간 압연하는 제2 단계, iii) 강판을 어닐링하는 제3 단계, 및 iv) 제2 단계 및 제3 단계를 반복하는 제4 단계를 포함한다. 제4 단계에서 강판을 어닐링하는 경우 강판의 어닐링 온도를 순차적으로 상승시킨다.

公开(公告)号：KR1020120072790A

公开(公告)日：2012-07-04

申请号：KR1020100134684

申请日：2010-12-24

Applicant: 한국과학기술연구원

Inventor： 에릭플러리 ,  김동익 ,  사트얌스와스 ,  서브하시스신하 ,  홍성민

IPC: C21D8/02 ,  C22C38/16

CPC classification number: C21D8/0205 ,  B21B3/02 ,  C21D6/00 ,  C21D8/0236 ,  C21D8/0273 ,  C21D2211/001 ,  C22C38/16

Abstract: PURPOSE: A copper-containing austenite stainless steel plate and a method for manufacturing the same are provided to obtain superior gain corrosion resistance through short-time annealing at low temperatures. CONSTITUTION: A method for manufacturing a copper-containing austenite stainless steel plate comprises the steps of: preparing a stainless steel plate containing copper of 1wt%-5wt%(S10), cold rolling the stainless steel plate(S20), annealing the stainless steel plate(S30), and repeating the cold rolling and annealing steps while gradually raising the annealing temperature(S40). In the initial cold rolling, the reduction ratio of the stainless steel plate is 3%-15%. The reduction ratio of the stainless steel plate after final rolling is 70%-90%.

Abstract translation: 目的：提供含铜奥氏体不锈钢板及其制造方法，以通过短时间退火在低温下获得优异的耐增蚀性。 构成：含铜奥氏体不锈钢板的制造方法包括以下步骤：制备含有1重量％〜5重量％的铜的不锈钢板（S10），冷轧不锈钢板（S20），对不锈钢进行退火 （S30），并且在逐渐提高退火温度的同时重复冷轧退火步骤（S40）。 在初始冷轧时，不锈钢板的减速比为3％-15％。 最终轧制后的不锈钢板的压下率为70％〜90％。

公开(公告)号：KR100378323B1

公开(公告)日：2003-03-29

申请号：KR1019990014356

申请日：1999-04-22

Applicant: 김용식 ,  정인원 ,  박주배 ,  한국과학기술연구원

Inventor： 김용식 ,  박주배 ,  안종석 ,  이현선 ,  정인원 ,  신철진 ,  오원근 ,  김시경 ,  강웅구 ,  홍성민

IPC: C07H13/08

CPC classification number: A61K31/704 ,  A61K36/69

Abstract: The present invention relates to psychotropic polygalasaponins and its extraction and isolation from the roots of Polygalae tenuifolia. The inhibitory activity of the extract from the roots of Polygalae tenuifolia on stereotyped behaviors and climbing behaviors induced by apomorphine was examined, and a single extract fraction that showed an activity particularly in behavioral pharmacology model was obtained from the roots of Polygalae tenuifolia. The object of the invention is therefore aimed at providing a new version of antipsychotic drug, polygalasaponic compound itself and a method to extract and isolate polygalasaponic compound from the roots of Polygalae Tenuifolia.

Abstract translation: 本发明涉及精神性多果皂苷及其从远志（Polygalae tenuifolia）根提取和分离。 研究了远志根部提取物对阿朴吗啡诱导的刻板行为和爬行行为的抑制活性，并从远志草的根部获得了一种特别在行为药理学模型中表现出活性的单一提取物部分。 因此，本发明的目的是提供一种新的抗精神病药物，多聚半乳糖化合物本身以及从远志藤根提取和分离多聚半乳糖化合物的方法。

公开(公告)号：KR1020000066933A

公开(公告)日：2000-11-15

申请号：KR1019990014356

申请日：1999-04-22

Applicant: 김용식 ,  정인원 ,  박주배 ,  한국과학기술연구원

Inventor： 김용식 ,  박주배 ,  안종석 ,  이현선 ,  정인원 ,  신철진 ,  오원근 ,  김시경 ,  강웅구 ,  홍성민

IPC: C07H13/08

CPC classification number: A61K31/704 ,  A61K36/69

Abstract: PURPOSE: A psychotropic polygalasaponin based compound is provided which inhibits a stereotyped behavior and climbing behavior which are induced by apomorphine. CONSTITUTION: A psychotropic polygalasaponin is represented by formula 1 representation. An extraction method are characterized by comprising the following steps: (i)after grinding Polygalae Radix up to 70-230 mesh, extracting three times with 3-5 fold amount of alcohol solution; (ii)evaporating and condensing the filtrate at 70-76 cm Hg and at 60-70°C; (iii)after suspending the condensate in distilled water of 10 fold volume ratio, shaking the above thing by adding alcohol solvent of 1-2 fold and extracting three times and separating alcohol layer; (iv)condensing the above alcohol solvent fraction at 70-76 cmHg and at 60-70°C and obtaining an extract; (v)after suspending the above extract with distilled water of 50-100 fold adsorbing in resin HP-20 and draining active material with 70% methanol and condensing for obtaining an extract; (vi)after condensing the above extract with distilled water of 50-100 fold 2-3 times in common ratio, suspending homogeneously with same amount of distilled water and freeze-drying for obtaining a powder extract; (vii)dissolving the powder extract in ether and obtaining a precipitate;(viii)after saturating the precipitate with distilled water, passing through HP-20 resin and eluting an active site with methanol and adsorbing in silica gel and eluting active material by using ethyl acetate/methanol/water; (ix)adsorbing the active material in silica gel again and fractionating with mixed solvent of trichloro methane/methanol/ethanol/10%-acetic acid.

Abstract translation: 目的：提供一种精神分析多聚赖草皂苷的化合物，其抑制由阿朴吗啡诱导的定型行为和攀爬行为。 构成：精神分裂多糖分子由式1表示。 提取方法的特征在于包括以下步骤：（i）研磨多达70-230目后，用3-5倍量的醇溶液萃取三次; （ii）在70-76cm Hg和60-70℃下蒸发并冷凝滤液; （iii）将冷凝物悬浮在10倍体积比的蒸馏水中后，加入1-2倍的酒精溶剂振荡上述物质，萃取3次，分离醇层; （iv）将上述醇溶剂级分在70-76cmHg和60-70℃下冷凝并得到提取物; （v）将吸附在树脂HP-20中的50-100倍的蒸馏水悬浮在上述提取物上，并用70％甲醇排出活性物质并冷凝得到提取物; （vi）将上述提取物与常规比例为50-100倍的蒸馏水冷凝2-3次后，用相同量的蒸馏水均匀悬浮，冷冻干燥得到粉末提取物; （vii）将粉末提取物溶解在乙醚中并获得沉淀物;（viii）在用蒸馏水使沉淀物饱和后，通过HP-20树脂并用甲醇洗脱活性位点并吸附在硅胶中，并用乙基 乙酸乙酯/甲醇/水; （ix）再次将活性物质吸附在硅胶中，并用三氯甲烷/甲醇/乙醇/ 10％乙酸的混合溶剂进行分馏。