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公开(公告)号：KR1020130125745A
公开(公告)日：2013-11-19
申请号：KR1020130133684
申请日：2013-11-05
Applicant: 한국과학기술연구원
IPC: A61K31/7034 , A61K31/7048 , A61P3/10 , A61P13/12
CPC classification number: Y02A50/478 , Y02A50/479 , A61K31/7048 , A23L33/125 , A61K31/704 , Y10S514/866
Abstract: The present invention provides a composition containing esculin, an esculin derivative, or a pharmaceutically acceptable salt or a solvate thereof as an active ingredient for reducing blood glucose. The present invention provides esculin, an esculin derivative, or a pharmaceutically acceptable salt or solvate thereof as an active ingredient for reducing creatinine in blood.
Abstract translation: 本发明提供含有作为降低血糖的活性成分的曲马素，七叶糖衍生物或其药学上可接受的盐或溶剂合物的组合物。 本发明提供了逃避血浆中的丝氨酸蛋白，七叶树素衍生物或其药学上可接受的盐或溶剂合物作为还原肌酸酐的活性成分。
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公开(公告)号：KR101439405B1
公开(公告)日：2014-09-11
申请号：KR1020120031250
申请日：2012-03-27
Applicant: 한국과학기술연구원
IPC: A61K36/8984 , A61P13/12
Abstract: 본 발명은 석곡 추출물을 유효성분으로 포함하여 신장 질환을 예방하거나 치료하는 조성물에 관한 것이다. 본 발명에 따른 조성물은 자연으로부터 얻어진 천연물을 유효성분으로 포함하여 인체에 적용시 부작용이 적을 뿐 아니라, 장기간 사용으로 인한 내성이 생길 가능성이 낮다. 특히, 본 발명의 조성물은 신장 세포의 보호에 있어서, 우수한 효능을 가지므로, 신장 질환의 예방 또는 치료에 있어서 유용하게 사용될 수 있다.
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Patent Agency Ranking
公开(公告)号：KR1020130083427A
公开(公告)日：2013-07-22
申请号：KR1020130080351
申请日：2013-07-09
Applicant: 한국과학기술연구원
IPC: A61K31/045 , A61K31/122 , A61K31/05 , A61P3/10
Abstract: PURPOSE: A composition for preventing, treating, or alleviating peroxisome proliferator-activated receptor (PPAR) action regulatory diseases is provided to promote PPAR activation and to prevent, treat, or alleviate the diseases including obesity, metabolic diseases, and cardiovascular diseases. CONSTITUTION: A pharmaceutical composition for preventing or treating PPAR action regulator diseases selected among diabetes, obesity, hyperinsulinemia, hyperlipidemia, hypercholesterolemia, hypertriglyceridemia, artery scleroma, and combination thereof contains a compound of chemical formula 1 or 2, or a pharmaceutically acceptable salt or a solvate thereof. A composition for health functional foods for preventing or treating the diseases contains the compound, the pharmaceutically acceptable salt, or the solvate.
Abstract translation: 目的：提供一种预防，治疗或减轻过氧化物酶体增殖物激活受体（PPAR）作用调节性疾病的组合物，用于促进PPAR活化并预防，治疗或减轻包括肥胖，代谢疾病和心血管疾病在内的疾病。 构成：用于预防或治疗选自糖尿病，肥胖症，高胰岛素血症，高脂血症，高胆固醇血症，高甘油三酯血症，动脉硬化及其组合的PPAR活性调节剂疾病的药物组合物含有化学式1或2的化合物或其药学上可接受的盐或 其溶剂合物。 用于预防或治疗疾病的健康功能性食品的组合物含有化合物，药学上可接受的盐或溶剂合物。
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公开(公告)号：KR101497109B1
公开(公告)日：2015-03-05
申请号：KR1020130080351
申请日：2013-07-09
Applicant: 한국과학기술연구원
IPC: A61K31/045 , A61K31/122 , A61K31/05 , A61P3/10
Abstract: 본 발명은 석곡(Dendrobium moniliforme)을 활성성분으로서 포함하는 PPAR(Peroxisome Proliferator-Activated Receptor) 작용 조절 질환의 예방 또는 치료용 약학 조성물 또는 건강기능식품용 조성물을 제공한다.
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公开(公告)号：KR1020130109504A
公开(公告)日：2013-10-08
申请号：KR1020120031261
申请日：2012-03-27
Applicant: 한국과학기술연구원
IPC: A61K31/7048 , A61K31/7034 , A61K31/70 , A61P3/10
CPC classification number: Y02A50/478 , Y02A50/479 , A61K31/7048 , A23L33/125 , A61K31/704 , Y10S514/866
Abstract: PURPOSE: A composition containing esculin is provided to prevent or treat diseases caused by hyperglycemia and renal diseases. CONSTITUTION: A composition for reducing blood glucose contains 0.001-10 wt% of esculin, an esculin derivative, a pharmaceutically acceptable salt thereof, or a solvate thereof as an active ingredient. The composition is a pharmaceutical composition or a health food composition. The composition is used for preventing or treating hyperglycemia or diabetes.
Abstract translation: 目的：提供含有esculin的组合物，以预防或治疗由高血糖症和肾脏疾病引起的疾病。 构成：用于降低血糖的组合物含有作为有效成分的三角蛋白的0.001-10重量％，七叶树素衍生物，其药学上可接受的盐或其溶剂合物。 该组合物是药物组合物或保健食品组合物。 该组合物用于预防或治疗高血糖或糖尿病。
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公开(公告)号：KR1020130109495A
公开(公告)日：2013-10-08
申请号：KR1020120031250
申请日：2012-03-27
Applicant: 한국과학기술연구원
IPC: A61K36/8984 , A61P13/12
CPC classification number: A61K36/8984 , A23L33/105 , A23V2002/00 , A23V2200/30
Abstract: PURPOSE: A composition containing Dendrobium moniliforme for preventing or treating renal diseases is provided to lessen side effects when the composition is applied to human body and to show less resistance even after long-term use. CONSTITUTION: A composition for preventing or treating renal diseases contains 0.001-10 wt% of a Dendrobium moniliforme extract as an active ingredient. The extract is a C1-C6 alcohol extract of Dendrobium moniliforme. C1-C6 alcohol is methanol or ethanol. The composition is used for reducing serum creatinine. [Reference numerals] (AA) Sell survival rate (%); (BB) Dendrobium monile
Abstract translation: 目的：提供一种用于预防或治疗肾脏疾病的含有石斛石斛的组合物，用于减轻组合物施用于人体时的副作用，即使长期使用后也显示出较低的抗性。 构成：用于预防或治疗肾脏疾病的组合物含有0.001-10重量％的石斛提取物作为活性成分。 提取物是石斛石斛的C1-C6醇提取物。 C1-C6醇是甲醇或乙醇。 该组合物用于降低血清肌酐。 （附图标记）（AA）销售存活率（％）; （BB）石斛石斛
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公开(公告)号：KR1020130047458A
公开(公告)日：2013-05-08
申请号：KR1020110112506
申请日：2011-10-31
Applicant: 한국과학기술연구원
IPC: A61K36/8984 , A61K31/045 , A61K31/047 , A61P3/04
CPC classification number: A61K36/8984 , A61K31/047 , A61K31/09 , A61K2236/333 , Y10S514/866 , Y10S514/909
Abstract: PURPOSE: A composition containing Dendrobium moniliforme is provided to prevent, relieve, or treat PPAR activation regulation-related diseases including obesity, metabolic diseases, and cardiovascular diseases. CONSTITUTION: A composition for preventing or treating PPAR activation regulation-related diseases contains Dendrobium moniliforme as an active ingredient. A composition for health functional food for preventing or treating PPAR activation regulation-related diseases contains Dendrobium moniliforme as an active ingredient. Dendrobium moniliforme is used as pulverized Dendrobium moniliforme, a dried material thereof, or a crude extract prepared by using a solvent which is selected from water, C1-C4 alcohol, and a combination thereof. The C1-C4 alcohol is methanol or ethanol. Dendrobium moniliforme is also used as a fraction which is prepared from the crude extract using n-hexane, methylene chloride, or ethyl acetate. [Reference numerals] (AA) Relative value(%); (BB) No treatment group, Troglitazone; (CC) Example ; (DD) Example ; (EE) Example n-Hx; (FF) Example MC; (GG) Example EA; (HH) Example fr2; (II) Example fr3; (JJ) Example fr2-2; (KK) Example fr2-5; (LL) Example compound 1; (MM) Example compound 2; (NN) Example compound 3; (OO) Example compound 4
Abstract translation: 目的：提供含有石斛仁的组合物，以预防，缓解或治疗PPAR活化调节相关疾病，包括肥胖，代谢疾病和心血管疾病。 构成：用于预防或治疗PPAR活化调节相关疾病的组合物含有石斛石斛作为活性成分。 用于预防或治疗PPAR活化调节相关疾病的健康功能性食品的组合物含有石斛兰作为活性成分。 石斛石斛被用作粉状石斛，其干燥物，或使用选自水，C1-C4醇及其组合的溶剂制备的粗提取物。 C1-C4醇是甲醇或乙醇。 石斛也用作由粗提取物使用正己烷，二氯甲烷或乙酸乙酯制备的级分。 （附图标记）（AA）相对值（％）; （BB）无治疗组，曲格列酮; （CC）实施例<1-1>; （DD）实施例<1-2>; （EE）实施例<2> n-Hx; （FF）实施例<2> MC; （GG）实施例
EA; （HH）实施例<3> fr2; （II）实施例<3> fr3; （JJ）实施例<3> fr2-2; （KK）实施例<3> fr2-5; （LL）实施例<3>化合物1; （MM）实施例3化合物2; （NN）实施例3化合物3; （OO）实例<3>化合物4
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