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    신규 간암 환자의 소라페닙 저항성 예측 마커
    1.
    发明申请
    신규 간암 환자의 소라페닙 저항성 예측 마커 审中-公开
    用于肝癌患者的新型抗抑郁药预防标记

    公开(公告)号：WO2016111507A1

    公开(公告)日：2016-07-14

    申请号：PCT/KR2016/000006

    申请日：2016-01-04

    Applicant: 서울대학교 산학협력단 ,  한국과학기술원

    Inventor： 윤정환 ,  유수종 ,  조광현 ,  원재경

    IPC: G01N33/574 ,  G01N33/68

    CPC classification number: G01N33/574 ,  G01N33/68

    Abstract: 본 발명은 새로운 바이오 마커에 관한 것으로서, 더 상세하게는 시료 내의 EDN1 단백질 또는 상기 EDN1 단백질을 암호화하는 mRNA의 수준을 검출할 수 있는 탐침분자를 유효성분으로 함유하는 간암 환자의 소라페닙 반응성 예측용 키트에 관한 것이다.

    Abstract translation: 本发明涉及一种新的生物标志物，更具体地说，涉及用于肝癌患者的索拉非尼反应性预测试剂盒，该试剂盒含有可检测样品内的EDN1蛋白或mRNA水平作为有效成分的探针分子 编码EDN1蛋白。

    한 개의 공전롤을 갖는 인발형 연속 전단변형장치
    3.
    发明授权
    한 개의 공전롤을 갖는 인발형 연속 전단변형장치 有权
    连续平均通道带有空心滚子的图形

    公开(公告)号：KR100778763B1

    公开(公告)日：2007-11-27

    申请号：KR1020060111404

    申请日：2006-11-13

    Applicant: 한국과학기술원

    Inventor： 양동열 ,  김경진 ,  윤정환

    IPC: B21C23/00

    Abstract: A drawing type continuous shear deformation equipment with an idle roll is provided to mass produce a workpiece with improved mechanical properties continuously by continuously performing a conventional ECAP(Equal Channel Angular Pressing) process and continuously supplying a metal workpiece to a shear deformation mold, thereby shear deforming the workpiece without limiting the length of the workpiece. A drawing type continuous shear deformation equipment(100) with an idle roll comprises: first upper and lower molds(120,130) for forming an inflow part into which a workpiece(170) flows; second upper and lower molds(140,150) which shear deforms the workpiece and forms a discharge part for discharging the shear deformed workpiece; an idle roll(110) disposed between the first upper and lower molds and the second upper and lower molds to form a shear deforming part in an outlet of the first upper and lower molds and an inlet of the second upper and lower molds respectively; and a drawing device for drawing out and transferring the workpiece.

    Abstract translation: 提供了一种具有空转辊的拉伸型连续剪切变形设备，通过连续执行常规的ECAP（等通道角度压制）工艺并连续地将金属工件供应到剪切变形模具，从而大量生产具有改善的机械性能的工件，从而剪切 使工件变形而不限制工件的长度。 具有空转辊的拉伸式连续剪切变形设备（100）包括：用于形成工件（170）流入的流入部分的第一上模具和下模具（120,130） 第二上下模具（140,150），其剪切工件变形并形成用于排出剪切变形工件的排出部分; 设置在所述第一上模具和下模具之间的空转辊（110）和所述第二上下模具，以分别在所述第一上下模具的出口和所述第二上模具和下模具的入口中形成剪切变形部件; 以及用于拉出和传送工件的拉丝装置。

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