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公开(公告)号：WO2019088348A1
公开(公告)日：2019-05-09
申请号：PCT/KR2017/014207
申请日：2017-12-06
Applicant: 한국과학기술원
IPC: A61K39/395 , A61K48/00 , A61K31/5377 , A61K31/517 , G01N33/50 , G01N33/68
Abstract: 본 발명은 본 발명은 신규 암 치료제에 관한 것으로서, GNB5에 특이적인 저해제 및 EGFR 저해제를 유효성분으로 포함하는 EGFR 저해제에 대한 저항성 암의 치료용 약학적 조성물을 제공한다.
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公开(公告)号：KR1020170007153A
公开(公告)日：2017-01-18
申请号：KR1020160085761
申请日：2016-07-06
Applicant: 울산대학교 산학협력단 , 한국과학기술원
Abstract: 본발명은원심캐스팅을이용한키틴나노섬유필름제조방법에관한것으로, 보다상세하게는키틴(Chitin) 원료를단일용액공정으로용액화시켜키틴용액을생성하는단계; 상기생성된키틴용액을원심캐스팅(Centrifugal casting) 공정을통해용매휘발에의한자기조립형(EISA: Evaporation-induced self-assemly) 키틴나노섬유필름(Chitin nanofiber film)을생성하는단계; 및상기생성된키틴나노섬유필름을기설정된온도및 압력으로진공가압을하여캘린더링처리하는단계를포함하는키틴나노섬유필름의제조방법을제공하고자한다.
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Patent Agency Ranking
公开(公告)号：KR102049090B1
公开(公告)日：2019-11-26
申请号：KR1020170184795
申请日：2017-12-29
Applicant: 한국과학기술원
IPC: A61K39/395 , A61K48/00 , A61K31/5377 , A61K31/517 , G01N33/50 , G01N33/68
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公开(公告)号：KR1020140118259A
公开(公告)日：2014-10-08
申请号：KR1020130033839
申请日：2013-03-28
Applicant: 한국과학기술원
IPC: G06F19/12
CPC classification number: G06F19/12 , G06F17/5009
Abstract: Disclosed is a bio-simulation method using a bio-simulation program using at least one cell-object, a cell-environment, and a bio-simulation regulation. In the method, a biological state which each cell-object expresses is determined by the cell-regulation corresponding to the cell-object. Each cell-regulation is embedded in the bio-simulation program with a DLL shape. Also, the cell-regulations are linked to GRN corresponding to the state of the cell-object. The GRN linked to each cell-regulation is replaced by different GRN according to the state change of the cell-object for network rewiring according to the state change of the cell-object.
Abstract translation: 公开了使用使用至少一个细胞对象，细胞环境和生物仿真调节的生物仿真程序的生物仿真方法。 在该方法中，每个细胞对象表达的生物学状态由与细胞对象相对应的细胞调节决定。 每个细胞调节嵌入到具有DLL形状的生物仿真程序中。 此外，细胞规则与细胞对象的状态相对应的GRN相关联。 根据细胞对象的状态变化，根据网络重新布线的细胞对象的状态变化，将不同的GRN替换为每个细胞调节链接的GRN。
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公开(公告)号：KR101847717B1
公开(公告)日：2018-05-28
申请号：KR1020160085761
申请日：2016-07-06
Applicant: 울산대학교 산학협력단 , 한국과학기술원
Abstract: 본발명은원심캐스팅을이용한키틴나노섬유필름제조방법에관한것으로, 보다상세하게는키틴(Chitin) 원료를단일용액공정으로용액화시켜키틴용액을생성하는단계; 상기생성된키틴용액을원심캐스팅(Centrifugal casting) 공정을통해용매휘발에의한자기조립형(EISA: Evaporation-induced self-assemly) 키틴나노섬유필름(Chitin nanofiber film)을생성하는단계; 및상기생성된키틴나노섬유필름을기설정된온도및 압력으로진공가압을하여캘린더링처리하는단계를포함하는키틴나노섬유필름의제조방법을제공하고자한다.
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公开(公告)号：KR1020140118258A
公开(公告)日：2014-10-08
申请号：KR1020130033837
申请日：2013-03-28
Applicant: 한국과학기술원
Abstract: The disclosed biosimulation method initiates a biosimulation by using one or more cell-objects, cell-environments, and biosimulation rules. A life-cycle which each cell-object represents is determined by a corresponding cell-rule. The method includes temporarily stopping the biosimulation by receiving a user interrupt; changing one or more corresponding cell-rules by receiving a user code; and reflecting the changed cell-rule to the biosimulation by using an embedded compiler included in a biosimulation program and compiling the user codes.
Abstract translation: 所公开的生物仿真方法通过使用一种或多种细胞对象，细胞环境和生物刺激规则来启动生物模拟。 每个单元对象表示的生命周期由相应的单元格规则确定。 该方法包括通过接收用户中断临时停止生物仿真; 通过接收用户代码来改变一个或多个相应的小区规则; 并通过使用包含在生物仿真程序中的嵌入式编译器并且编译用户代码来将改变的细胞规则反映到生物模拟中。
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