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公开(公告)号：KR1019930001383B1
公开(公告)日：1993-02-27
申请号：KR1019900017551
申请日：1990-10-31
Applicant: 한국화학연구원
IPC: C12N1/20
Abstract: Biologically pure cultures of Bacillus subtilis subsp. Krictiensis (ATCC 55079) and of its mutant M18-91 (ATCC 55078) are new. The new microorganisms produce the antifungal complex KRF-001 which is useful as an agricultural or therapeutic fungicide, food preservative or skin moisturizer. KRF-001 is an oligopeptide and has a broad spectrum of activity and low toxicity.
Abstract translation: 生物纯培养的枯草芽孢杆菌 Krictiensis（ATCC 55079）及其突变体M18-91（ATCC 55078）是新的。 新的微生物产生用作农业或治疗杀真菌剂，食品防腐剂或皮肤保湿剂的抗真菌复合物KRF-001。 KRF-001是一种寡肽，具有广谱活性和低毒性。
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公开(公告)号：KR1020020007014A
公开(公告)日：2002-01-26
申请号：KR1020000040668
申请日：2000-07-14
IPC: A61K31/343
Abstract: PURPOSE: Provided is a cell growth regulator composition containing cryptotanshinone as active ingredient. Particularly, the cryptotanshinone has an excellent selective inhibition effect on cyclin dependent kinas 4(CDK4) and is thus used for drug preparations for the treatment and prevention of various diseases. CONSTITUTION: The cell growth regulator composition characteristically contains Cryptotanshinone represented by the formula(1) selectively inhibiting the activity of CDK4/cyclin D and a pharmaceutically acceptable carrier. It inhibits the cell growth and is thus ultimately used in developing drug preparations for the prevention and treatment of various diseases caused by abnormal cell cycle.
Abstract translation: 目的：提供含有隐丹参酮作为活性成分的细胞生长调节剂组合物。 特别地，隐丹参酮对细胞周期蛋白依赖性激酶4（CDK4）具有优异的选择性抑制作用，因此用于治疗和预防各种疾病的药物制剂。 构成：细胞生长调节剂组合物特征性地含有由式（1）表示的隐丹参酮选择性抑制CDK4 /细胞周期蛋白D的活性和药学上可接受的载体。 它抑制细胞生长，因此最终用于开发用于预防和治疗由异常细胞周期引起的各种疾病的药物制剂。
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公开(公告)号：KR1019930001870B1
公开(公告)日：1993-03-18
申请号：KR1019900017552
申请日：1990-10-31
Applicant: 한국화학연구원
IPC: C12P1/04
Abstract: Biologically pure cultures of Bacillus subtilis sub sp. Krictiensis (ATCC 55079) and of its mutant M18-91 (ATCC 55078) are new. The new microorganisms produce the antifungal complex KRF-001 (disclosed as new but not claimed) which is useful as an agricultural or therapeutic fungicide, food presevative or skin moisturiser. It has a broad spectrum of activity and low toxicity.
Abstract translation: 枯草芽孢杆菌属的生物纯培养物 Krictiensis（ATCC 55079）及其突变体M18-91（ATCC 55078）是新的。 新的微生物产生可用作农业或治疗杀真菌剂，食品预防剂或皮肤保湿剂的抗真菌复合物KRF-001（公开为新的但未被要求保护）。 它具有广泛的活性和低毒性。
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Patent Agency Ranking
公开(公告)号：KR100145740B1
公开(公告)日：1998-08-01
申请号：KR1019910008328
申请日：1991-05-23
Applicant: 한국화학연구원
IPC: A01N63/02
CPC classification number: A01N63/00 , A01N63/04 , A01N25/24 , A01N25/10 , A01N2300/00
Abstract: 본 발명의 길항 미생물을 대사성 고분자를 함유하는 천연물이나 그의 가공물 또는 유도체로 이루어진 담체에 고정화시켜서 되어진 무공해성이고 경제적인 고정화 미생물 농약을 제공하는 것이다. 또한 본 발명의 그러한 고정하 미생물 농약을 제조하는 방법과, 그러한 고정화 미생물을 이용하는 방법에 관한 것이다.
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