公开(公告)号：KR1020090067490A

公开(公告)日：2009-06-25

申请号：KR1020070135167

申请日：2007-12-21

Applicant: 한국화학연구원

Inventor： 김영섭 ,  유시용 ,  연규환 ,  유대석 ,  최연희 ,  원무호 ,  황인구 ,  유기연

IPC: A61K36/346 ,  A61P9/10

Abstract: A pharmaceutical composition for preventing and treating ischemic cerebrovascular diseases, which contains old platycodon extract is provided to prevent the damage of nerve cell in the area of hippocampus anatomy and inhibit nerve cell apoptosis. A composition for preventing and treating ischemic cerebrovascular diseases comprises 0.1-90 weight% of Platycodon grandiflorum extract as an active ingredient. The ischemic cerebrovascular diseases are stroke, cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, white matter dyslipidemia, brain hypoxia, alzheimer disease, parkinson's disease or Huntington disease. The Platycodon grandiflorum extract is obtained with water, C1-4 alcohol, ethylacetate, hexane or dichloromethane.

Abstract translation: 提供含有老桔梗提取物的预防和治疗缺血性脑血管疾病的药物组合物，以防止神经细胞在海马解剖学领域的损伤并抑制神经细胞凋亡。 用于预防和治疗缺血性脑血管病的组合物含有0.1-90重量％的桔梗提取物作为活性成分。 缺血性脑血管病是中风，脑梗死，脑出血，蛛网膜下腔出血，白质血脂异常，脑缺氧，阿尔茨海默病，帕金森病或亨廷顿疾病。 用水，C 1-4醇，乙酸乙酯，己烷或二氯甲烷获得桔梗提取物。