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公开(公告)号:KR1020070084933A
公开(公告)日:2007-08-27
申请号:KR1020060017326
申请日:2006-02-22
Applicant: 한국화학연구원
Abstract: An extract of Cucumis sativus L. is provided to remove the toxicity of paraquat completely and show excellent active oxygen species(such as hydrogen peroxide, superoxide anion and hydroxyl radical) scavenging activity, thereby being used for an antioxidant composition. The antioxidant composition comprises an extract of Cucumis sativus L. as an effective ingredient. The method for preparing the extract comprises the steps of: (a) extracting Cucumis sativus L. with at least one solvent selected from the group consisting of methanol, ethanol, propanol, and chloroform and concentrating it under reduced pressure; (b) respectively fractionating the concentrate with hexane, ethyl ether, ethyl acetate, butanol and water; and (c) performing silica gel column chromatography, Sep-Pack C18 cartridge and HPLC in sequence on fractions obtained from the step(b).
Abstract translation: 提供黄瓜提取物,以完全消除百草枯的毒性,并显示出优异的活性氧(如过氧化氢,超氧阴离子和羟基自由基)清除活性,从而用于抗氧化剂组合物。 抗氧化剂组合物包含作为有效成分的黄瓜提取物。 制备提取物的方法包括以下步骤:(a)用至少一种选自甲醇,乙醇,丙醇和氯仿的溶剂提取黄瓜,并在减压下浓缩; (b)分别用己烷,乙醚,乙酸乙酯,丁醇和水分离浓缩物; 和(c)按步骤(b)得到的级分依次进行硅胶柱层析,Sep-Pack C18柱和HPLC。
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公开(公告)号:KR100829596B1
公开(公告)日:2008-05-14
申请号:KR1020060017326
申请日:2006-02-22
Applicant: 한국화학연구원
Abstract: 본 발명은 항산화 활성을 갖는 오이 초본 추출물에 관한 것으로서, 더욱 상세하게는 오이(
Cucumis sativus L.) 초본(어린잎) 추출물이 파라콰트의 독성을 완전히 제거하고, 과산화수소(hydrogen peroxide), 초과산화음이온(superoxide anion), 수산기라디칼(hydroxyl radical) 등의 활성산소종별 소거활성이 우수하여 강한 항산화 활성을 가짐을 밝힘으로써 오이 초본 추출물을 함유하는 항산화 조성물에 관한 것이다.
항산화 활성, 오이 초본, 파라콰트, 과산화수소, 초과산화음이온
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