황반변성 예방 또는 치료용 약학 조성물
    6.
    发明公开
    황반변성 예방 또는 치료용 약학 조성물 审中-实审
    用于预防或治疗谷物变性的药物组合物

    公开(公告)号:KR1020120112162A

    公开(公告)日:2012-10-11

    申请号:KR1020120032161

    申请日:2012-03-29

    CPC classification number: A61K9/0048 A61K31/4178

    Abstract: PURPOSE: A pharmaceutical composition containing secondary amine-substituted benzopyrane derivative is provided to prevent or treat macular degeneration. CONSTITUTION: A pharmaceutical composition for preventing or treating macular degeneration contains a compound of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. The composition is used in the form of eye drops and the active ingredients are delivery to retina. Eye drops for preventing or treating macular degeneration contain the compound of chemical formula 1 or pharmaceutically acceptable salt thereof as an active ingredient. A pharmaceutical composition for preventing or treating macular degeneration contains (2R,3R,4S)-6-amino-4-[N-(4-chlorophenyl)-N-(1H-imidazole-2-ylmethyl)amino]-3-hydroxy-2-methyl-2-dimethoxymethyl-3,4-dihydro-2H-1-benzopyrane or pharmaceutically acceptable salt thereof as an active ingredient.

    Abstract translation: 目的:提供含有仲胺取代苯并吡喃衍生物的药物组合物,用于预防或治疗黄斑变性。 构成:用于预防或治疗黄斑变性的药物组合物含有化学式1的化合物或其药学上可接受的盐作为活性成分。 组合物以眼药水的形式使用,活性成分被输送到视网膜。 用于预防或治疗黄斑变性的眼药水含有化学式1的化合物或其药学上可接受的盐作为活性成分。 用于预防或治疗黄斑变性的药物组合物含有(2R,3R,4S)-6-氨基-4- [N-(4-氯苯基)-N-(1H-咪唑-2-基甲基)氨基] -3-羟基 -2-甲基-2-二甲氧基甲基-3,4-二氢-2H-1-苯并吡喃或其药学上可接受的盐作为活性成分。

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