Abstract:
본 발명은 알츠하이머질병(Alzheimer's Disease)의 예방, 치료 및 인지능 개선을 목적으로 생더덕과 찐더덕 추출물 및 분획물은 아세틸콜린에스터라제의 활성을 저해함으로써 뇌에서 분비되는 아세틸콜린의 농도를 증가시켜, 콜린성 신경기능 퇴화로 인한 알츠하이머병의 예방 및 치료에 효과적이다. 또한 생더덕과 찐더덕 추출물 및 분획물을 포함하는 것을 특징으로 하는 치매 예방 또는 치료 및 인지능 개선용 약학적 조성물 또는 기능성 식품 조성물에 관한 것이다.
Abstract:
PURPOSE: A composition containing Ligularia fischeri extract or fraction thereof is provided to safely treat diabetic complication without toxicity and side effects. CONSTITUTION: A composition for preventing or treating diabetic complication contains Ligularia fischeri extract prepared by extracting Ligularia fischeri using water, straight or branched alcohol of C1-C4, or a mixture thereof, or Ligularia fischeri fraction prepared by fractioning the Ligularia fischeri extract with water, hexane, methylene chloride, ethyl acetate, or butanol. A composition for preventing or treating diabetes or diabetic complication contains the extract or fraction as an active ingredient.
Abstract:
PURPOSE: A composition containing extracts and fractions of raw and steamed Codonopsis lanceolata is provided to enhance acetyl choline concentration in a brain and to effectively prevent and treat Alzheimer's disease. CONSTITUTION: A pharmaceutical composition or a functional food composition for preventing or treating dementia contains extracts and fractions of raw and steamed Codonopsis lanceolata. The extracts are prepared using 70% ethanol. The raw and steamed Codonopsis lanceolata helps neurotransmission of acetyl choline by suppressing acetyl choline esterase. A composition for preventing and treating neurodegenerative diseases contains 0.1-99 wt% of the extracts and fractions as active ingredients and a pharmaceutically acceptable carrier.