公开(公告)号：KR1020100041258A

公开(公告)日：2010-04-22

申请号：KR1020080100363

申请日：2008-10-13

Applicant: 황재관

Inventor： 권송희 ,  이관형 ,  김능배 ,  김성경 ,  황재관

IPC: A61K31/357 ,  A61P31/04

Abstract: PURPOSE: A composition containing JS-1 or Baeckea frutescens L. extract is provided to use in acne treatment with excellent antibacterial activity. CONSTITUTION: An antibacterial composition contains JS-1 compound of chemical formula 1 or its pharmaceutically acceptable salt as an active ingredient. The composition has antibacterial activity to Propionibacterium acnes, Staphylococcus epidermidis, Micrococcus luteus, Staphylococcus aureus, Staphylococcus warneri, Staphylococcus haemolyticus, Staphylococcus xylosus, Staphylococcus hominis or Staphylococcus saprophyticus. The JS-1 of chemical formula 1 is isolated from Baeckea frutescens L. The antibacterial composition contains Baeckea frutescens L. extract as an active ingredient. The Baeckea frutescens L. extract is isolated using water, organic solvent of C1-C6, subcritical water, or supercritical carbon dioxide. A composition for treating acne contains the JS-1 compound of chemical formula 1 or its pharmaceutically acceptable salt as an active ingredient.

Abstract translation: 目的：提供含有JS-1或Baeckea frutescens L.提取物的组合物，用于具有优异抗菌活性的痤疮治疗。 构成：抗菌组合物含有化学式1的JS-1化合物或其药学上可接受的盐作为活性成分。 该组合物对痤疮丙酸杆菌，表皮葡萄球菌，金黄色葡萄球菌，金黄色葡萄球菌，溶血葡萄球菌，木葡萄球菌，人葡萄球菌或腐生葡萄球菌具有抗菌活性。 化学式1的JS-1分离自Baeckea frutescens L.抗菌组合物含有Baeckea frutescens L.提取物作为活性成分。 使用水，C1-C6的有机溶剂，亚临界水或超临界二氧化碳分离Baeckea frutescens L.提取物。 用于治疗痤疮的组合物含有化学式1的JS-1化合物或其药学上可接受的盐作为活性成分。