公开(公告)号：KR1020010112817A

公开(公告)日：2001-12-22

申请号：KR1020000033083

申请日：2000-06-15

Applicant: 황재관

Inventor： 황재관 ,  박보선

IPC: C07D311/62

Abstract: Synthesis of the MDRI of formula (I) from intermediates of acridone acid of formula (II) and aminophenethyl isoquinoline of formula (III), via steps including coupling and conversion to yield the MDRI of formula (I).

Abstract translation: 通过式（II）的吖啶酮和式（III）的氨基苯乙基异喹啉的中间体，通过偶联和转化的步骤合成式（I）的MDRI，得到式（I）的MDRI。

公开(公告)号：KR1020010091872A

公开(公告)日：2001-10-23

申请号：KR1020000067244

申请日：2000-11-13

Applicant: 황재관

Inventor： 황재관 ,  박보선 ,  최문정

IPC: A23L1/10

Abstract: PURPOSE: The physiologically active substances isolated from grains and a producing method thereof are provided to easily and readily produce the physiologically active substances. CONSTITUTION: The physiologically active substances isolated from grains comprises the steps of: inserting grains into an extruder and extruding them under conditions: 200 to 400 rpm of screw speed, 20 to 50 kg/hour of grain inserting rate, 15 to 40% of humidity and 100 to 200 deg. C of heating temperature; adding hydrolases into the extrudates in a weight ratio of 1:0.0001 to 1:1 and reacting them at 30 to 60 deg. C for 5 to 24 hours; and drying the enzyme hydrolyzed grains in a drum dryer at 40 to 90 deg. C for 10 to 20 hours. Wherein, the grains are selected from the outer surfaces of rice, barely, wheat, corn, job's tear, buckwheat and rye, and the hydrolases are selected from cellulase, arabinase, mannase and glucanase.

Abstract translation: 目的：提供从谷物中分离的生理活性物质及其制备方法容易且容易地产生生理活性物质。 构成：从颗粒中分离的生理活性物质包括以下步骤：将颗粒插入挤出机中并在螺杆速度为200至400rpm，颗粒插入速率为20至50kg /小时，湿度为15至40％的条件下挤出 和100〜200度。 加热温度℃; 以1：0.0001至1：1的重量比将水解酶加入到挤出物中，并使它们在30至60℃下反应。 C为5〜24小时; 并在40至90度的烘缸中干燥酶水解的颗粒。 C 10〜20小时。 其中，谷物选自水稻，勉强，小麦，玉米，工作眼泪，荞麦和黑麦的外表面，水解酶选自纤维素酶，阿拉伯聚糖酶，甘露聚糖酶和葡聚糖酶。

公开(公告)号：KR1020000000256A

公开(公告)日：2000-01-15

申请号：KR1019990043143

申请日：1999-10-06

Applicant: 황재관

Inventor： 황재관 ,  심재석 ,  박보선 ,  변유량

IPC: A61K8/97 ,  A61Q19/00

Abstract: PURPOSE: An antibiotic agent is provided to selectively kill the microorganisms that cause the pimple and skin problems. CONSTITUTION: An antibiotic agent comprises the steps of: extracting the Curcuma xanthorrhiza Roxb dried and shattered using water, methanol, ethanol, ethyl-acetate, hexane or compound solvent of those; putting 0.01-5wt% of the extract by extracting antibiotic active material only in the whole composition.

Abstract translation: 目的：提供抗生素以选择性地杀死引起疙瘩和皮肤问题的微生物。 构成：抗生素剂包括以下步骤：使用水，甲醇，乙醇，乙酸乙酯，己烷或其混合溶剂将姜黄黄疸Roxb干燥并粉碎; 通过仅在整个组合物中提取抗生素活性物质，提取0.01-5wt％的提取物。

公开(公告)号：KR100379582B1

公开(公告)日：2003-04-08

申请号：KR1020000067244

申请日：2000-11-13

Applicant: 황재관

Inventor： 황재관 ,  박보선 ,  최문정

IPC: A23L1/10

Abstract: PURPOSE: The physiologically active substances isolated from grains and a producing method thereof are provided to easily and readily produce the physiologically active substances. CONSTITUTION: The physiologically active substances isolated from grains comprises the steps of: inserting grains into an extruder and extruding them under conditions: 200 to 400 rpm of screw speed, 20 to 50 kg/hour of grain inserting rate, 15 to 40% of humidity and 100 to 200 deg. C of heating temperature; adding hydrolases into the extrudates in a weight ratio of 1:0.0001 to 1:1 and reacting them at 30 to 60 deg. C for 5 to 24 hours; and drying the enzyme hydrolyzed grains in a drum dryer at 40 to 90 deg. C for 10 to 20 hours. Wherein, the grains are selected from the outer surfaces of rice, barely, wheat, corn, job's tear, buckwheat and rye, and the hydrolases are selected from cellulase, arabinase, mannase and glucanase.

Abstract translation: 目的：提供从谷物中分离的生理活性物质及其生产方法，以容易且容易地生产生理活性物质。 组成：从谷物中分离出的生理活性物质包括以下步骤：将谷物插入挤压机中并在螺杆速度为200至400rpm，谷粒插入率为20至50kg /小时，湿度为15至40％ 和100至200度。 加热温度C; 以1:0.0001至1:1的重量比将水解酶加入挤出物中，并在30至60℃下使它们反应。 C 5至24小时; 并在40至90℃下在滚筒式干燥器中干燥酶水解的谷物。 C 10至20小时。 其中，谷物选自米，勉强，小麦，玉米，工作眼泪，荞麦和黑麦的外表面，并且水解酶选自纤维素酶，阿拉伯酶，甘露聚糖酶和葡聚糖酶。