MICRONEEDLE DEVICES AND METHODS OF MANUFACTURE
    2.
    发明申请
    MICRONEEDLE DEVICES AND METHODS OF MANUFACTURE 审中-公开
    MICRONEEDLE设备及其制造方法

    公开(公告)号:WO2003059431A1

    公开(公告)日:2003-07-24

    申请号:PCT/US2002/037920

    申请日:2002-11-26

    Abstract: Microneedle devices and methods of manufacturing the microneedle devices. The microneedle devices include microneedles protruding from a substrate (20), with the microneedles (30) piercing a cover (40) placed over the substrate surface (22) from which the microneedles protrude. The cover (40) and the microneedle substrate (20) together define a capillary volume in fluid communication with the base (34) of each microneedle (30). One manner of using microneedle arrays of the present invention is in methods involving the penetration of skin to deliver medicaments or other substances and/or extract blood or tissue. Manufacturing methods may include simultaneous application of pressure and ultrasonic energy when piercing the cover with the microneedles.

    Abstract translation: 微针装置和制造微针装置的方法。 微针装置包括从基板(20)突出的微针,其中微针(30)刺穿放置在基板表面(22)上的盖(40),微针从该突出部突出。 覆盖物(40)和微针衬底(20)一起限定了与每个微针(30)的基部(34)流体连通的毛细管体积。 使用本发明的微针阵列的一种方式是涉及皮肤渗透以递送药物或其它物质和/或提取血液或组织的方法。 制造方法可以包括在用微针刺穿盖时同时施加压力和超声能量。

    POLYMER PHOTONIC CRYSTAL FIBERS
    8.
    发明申请
    POLYMER PHOTONIC CRYSTAL FIBERS 审中-公开
    聚合物光子晶体纤维

    公开(公告)号:WO2006093627A1

    公开(公告)日:2006-09-08

    申请号:PCT/US2006/004128

    申请日:2006-02-03

    Abstract: A composite polymer fiber comprises a polymer filler material and a plurality of polymer scattering fibers disposed within the filler material. At least one of the filler material and the scattering fibers is formed of a birefringent material. The refractive indices of the filler material and the scattering fibers can be substantially matched for light incident in a first polarization state on the composite polymer fiber and unmatched for light incident in an orthogonal polarization state. The scattering fibers may be arranged to form a photonic crystal within the composite fiber. The composite fibers may be extruded and may be formed into a yarn, a weave or the like. If the filler material is soluble, it may be washed out of the yarn or weave, and the scattering fibers may then be infiltrated with a resin that is subsequently cured.

    Abstract translation: 复合聚合物纤维包括聚合物填充材料和布置在填充材料内的多个聚合物散射纤维。 填充材料和散射纤维中的至少一种由双折射材料形成。 对于在复合聚合物纤维上以第一偏振状态入射的光,填充材料和散射光纤的折射率可以基本上匹配,并且对于以正交偏振状态入射的光是不匹配的。 散射纤维可以被布置成在复合纤维内形成光子晶体。 复合纤维可以被挤出并且可以形成为纱线,编织物等。 如果填充材料是可溶的,则其可以从纱线中洗涤或织出,然后散射纤维可以用随后固化的树脂渗透。

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