公开(公告)号：US20040214851A1

公开(公告)日：2004-10-28

申请号：US10832737

申请日：2004-04-27

Applicant: 3M Innovative Properties Company

Inventor： Woubalem M.R. Birmachu ,  Herbert B. Slade ,  John C. Stolpa ,  Mirjana Urosevic

IPC: A61K031/4745

CPC classification number: A61K51/1027 ,  A61K31/4745 ,  A61K38/08 ,  A61K39/395 ,  A61K45/06 ,  A61K47/6849 ,  A61K51/103 ,  A61K51/1036 ,  A61K2300/00

Abstract: The present invention provides compositions and method for increasing expression of opioid receptors. Generally, the compositions include and opioid receptor inducing compound and, optionally, an opioid receptor ligand. Generally, the methods include contacting a cell with an amount of an opioid receptor inducing compound effective for inducing expression of the opioid receptor and, optionally, contacting the cell with an opioid receptor ligand.

Abstract translation: 本发明提供了增加阿片受体表达的组合物和方法。 通常，组合物包括和阿片受体诱导化合物和任选的阿片受体配体。 通常，所述方法包括使细胞与一定量的阿片受体诱导化合物接触，所述化合物有效诱导阿片受体的表达，并且任选地使细胞与阿片受体配体接触。