公开(公告)号：EP0405506A1

公开(公告)日：1991-01-02

申请号：EP90112261.4

申请日：1990-06-27

Applicant: ABBOTT LABORATORIES

Inventor： Chung, John Y.-L. ,  Tufano, Michael D. ,  May, Paul D. ,  Shiosaki, Kazumi ,  Nadzan, Alex M. ,  Garvey, David S. ,  Shue, Youe-Kong ,  Brodie, Mark S. ,  Holladay, Mark W.

IPC: C07K5/00 ,  A61K37/02

CPC classification number: C07K5/1016 ,  A61K38/00 ,  C07K5/0207 ,  C07K5/0808 ,  C07K5/1024

Abstract: A tetrapeptide type-B CCK receptor ligand of the formula
A-B-C-D
or a pharmaceutically acceptable salt thereof, which is useful for treating central nervous system disorders, substance abuse, gastrointestinal disorders, endocrine disorders, eating-related disorders and treatment of shock, respiratory and cardiocirculatory insufficiencies.

Abstract translation: 用于治疗中枢神经系统疾病，药物滥用，胃肠道疾病，内分泌紊乱，进食相关疾病和休克，呼吸和心脏循环治疗的ABCD的四肽B型CCK受体配体或其药学上可接受的盐 不足。