公开(公告)号：WO2003090761A1

公开(公告)日：2003-11-06

申请号：PCT/US2003/012478

申请日：2003-04-23

Applicant: ABBOTT LABORATORIES

Inventor： SEARLE, Xenia, Beebe ,  DJURIC, Stevan ,  MA, Zhenkun ,  YANG, Fan

IPC: A61K31/7048

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

Abstract translation: 公开了具有式（I）的抗菌化合物及其前体药物的前体药物及其盐，制备本方法中使用的化合物和中间体的方法，含该化合物的组合物，以及使用该化合物预防或治疗细菌感染的方法 。

公开(公告)号：WO2003068790A3

公开(公告)日：2003-08-21

申请号：PCT/US2003/004117

申请日：2003-02-11

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  CLARK, Richard ,  DJURIC, Stevan ,  WANG, Sanyi

IPC: C07H17/08

Abstract: Antibacterial compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

公开(公告)号：WO2003090679A3

公开(公告)日：2003-11-06

申请号：PCT/US2003/012590

申请日：2003-04-24

Applicant: ABBOTT LABORATORIES

Inventor： CLARK, Richard ,  DJURIC, Stevan ,  MA, Zhenkun ,  WANG, Sanyi

IPC: C07H17/08

Abstract: Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

公开(公告)号：WO2003068791A3

公开(公告)日：2003-08-21

申请号：PCT/US2003/004130

申请日：2003-02-11

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  KEYES, Robert ,  DJURIC, Stevan ,  YONG, Hong

IPC: C07H17/08

Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis and treatment of MRSA infections using the compounds are disclosed.

公开(公告)号：WO2003068790A2

公开(公告)日：2003-08-21

申请号：PCT/US2003/004117

申请日：2003-02-11

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  CLARK, Richard ,  DJURIC, Stevan ,  WANG, Sanyi

IPC: C07H17/00

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

Abstract translation: 具有式（I）的抗菌化合物及其盐，前药和前药的盐，制备用于该方法的化合物和中间体的方法，含有该化合物的组合物，以及预防或治疗 披露了使用这些化合物的细菌感染。

公开(公告)号：WO2002032919A3

公开(公告)日：2002-04-25

申请号：PCT/US2001/032278

申请日：2001-10-16

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  PHAM, Ly, Tam ,  CLARK, Richard, F. ,  ZHANG, Souming ,  DJURIC, Stevan

IPC: C07H17/08

Abstract: Compounds having formula (I) are useful for treating bacterial infections while avoiding the concomitant liability of gastrointestinal intolerance. Compositions containing the compounds and methods of treatment using the compounds are also disclosed.

公开(公告)号：WO2003090760A1

公开(公告)日：2003-11-06

申请号：PCT/US2003/012461

申请日：2003-04-23

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  DJURIC, Stevan ,  FLORJANCIC, Alan, S. ,  YONG, Hong ,  GU, YUGUI

IPC: A61K31/7048

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates employed in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections in a fish or a mammal using the compounds are disclosed.

Abstract translation: 具有式（I）和式（II）的抗菌化合物及其前体药物的盐，前药和盐，用于制备本方法中使用的化合物和中间体的方法，含有该化合物的组合物，以及预防或治疗细菌感染的方法 公开了使用该化合物的鱼或哺乳动物。

公开(公告)号：WO2003068791A2

公开(公告)日：2003-08-21

申请号：PCT/US2003/004130

申请日：2003-02-11

Applicant: ABBOTT LABORATORIES

Inventor： MA, Zhenkun ,  KEYES, Robert ,  DJURIC, Stevan ,  YONG, Hong

IPC: C07H17/00

CPC classification number: C07H17/08

Abstract: Compounds having activity against methicillin-resistant staphylococcus aureus (MRSA), the compounds having formula (I), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis and treatment of MRSA infections using the compounds are disclosed.

Abstract translation: 具有抗甲氧西林抗性金黄色葡萄球菌（MRSA）活性的化合物，具有式（I）的化合物及其前体药物的盐，前体药物和盐，用于制备该方法中使用的化合物和中间体的方法，包含该化合物的组合物和 公开了使用该化合物预防和治疗MRSA感染的方法。

公开(公告)号：EP1501847A2

公开(公告)日：2005-02-02

申请号：EP03733878.7

申请日：2003-04-24

Applicant: Abbott Laboratories

Inventor： CLARK, Richard ,  DJURIC, Stevan ,  MA, Zhenkun ,  WANG, Sanyi

IPC: C07H17/08

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates used in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections using the compounds are disclosed.

Abstract translation: 具有式（I）和式（II）的抗菌化合物及其盐，前药和前药的盐，制备用于该方法的化合物和中间体的方法，含有该化合物的组合物，以及预防或治疗细菌感染 公开了使用这些化合物。

公开(公告)号：EP1499326A1

公开(公告)日：2005-01-26

申请号：EP03719889.2

申请日：2003-04-23

Applicant: Abbott Laboratories

Inventor： MA, Zhenkun ,  DJURIC, Stevan ,  FLORJANCIC, Alan, S. ,  YONG, Hong ,  GU, YUGUI

IPC: A61K31/7048 ,  C07H17/08

CPC classification number: C07H17/08

Abstract: Antibacterial compounds having formula (I) and formula (II), and salts, prodrugs, and salts of prodrugs thereof, processes for making the compounds and intermediates employed in the processes, compositions containing the compounds, and methods for prophylaxis or treatment of bacterial infections in a fish or a mammal using the compounds are disclosed.