公开(公告)号：EP0663912A1

公开(公告)日：1995-07-26

申请号：EP93923826.0

申请日：1993-10-08

Applicant: ABBOTT LABORATORIES

Inventor： ABREO, Melwyn A. ,  GUNN, David E. ,  LIN, Nan-Horng ,  ELLIOTT, Richard L. ,  GARVEY, David S. ,  LEBOLD, Suzanne A. ,  WASICAK, James T.

IPC: A61K31 ,  A61P25 ,  C07D401 ,  C07D403 ,  C07D411 ,  C07D417 ,  C07D471 ,  C07D487

CPC classification number: C07D401/12 ,  C07D403/12 ,  C07D417/12

Abstract: Novel heterocyclic ether compounds of formula (I), wherein A, B and R2 are specifically defined, or pharmaceutically-acceptable salts or prodrugs thereof, which are selective and potent ligands at cholinergic channel receptors, useful in the treatment of cognitive, neurological and mental disorders characterized by decreased cholinergic function.

公开(公告)号：EP0663912B1

公开(公告)日：2001-12-12

申请号：EP93923826.7

申请日：1993-10-08

Applicant: ABBOTT LABORATORIES

Inventor： ABREO, Melwyn A. ,  GUNN, David E. ,  LIN, Nan-Horng ,  ELLIOTT, Richard L. ,  GARVEY, David S. ,  LEBOLD, Suzanne A. ,  WASICAK, James T.

IPC: C07D401/12 ,  C07D403/12 ,  C07D411/12 ,  A61K31/425 ,  A61K31/44 ,  A61K31/445 ,  A61K31/47 ,  A61K31/495 ,  A61K31/50 ,  A61K31/505 ,  C07D417/12 ,  C07D487/04 ,  C07D453/02

CPC classification number: C07D401/12 ,  C07D403/12 ,  C07D417/12

Abstract: Novel heterocyclic ether compounds of formula (I), wherein A, B and R2 are specifically defined, or pharmaceutically-acceptable salts or prodrugs thereof, which are selective and potent ligands at cholinergic channel receptors, useful in the treatment of cognitive, neurological and mental disorders characterized by decreased cholinergic function.