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公开(公告)号：WO2012027440A1
公开(公告)日：2012-03-01
申请号：PCT/US2011/048910
申请日：2011-08-24
Applicant: ABBOTT LABORATORIES , BELK, Jonathan , BROPHY, Susan , HUANG, Dagang , TIEMAN, Bryan , SCHEFFEL, James , TYNER, Joan , ZIEMANN, Robert
Inventor： BELK, Jonathan , BROPHY, Susan , HUANG, Dagang , TIEMAN, Bryan , SCHEFFEL, James , TYNER, Joan , ZIEMANN, Robert
CPC classification number: C07K16/1054 , C07K2317/92 , G01N33/56988
Abstract: This invention relates to novel antibodies that can be used in the detection of human immunodeficiency virus (HIV). These antibodies exhibit a high degree of sensitivity and are believed to provide broad range of specificity. The antibodies can be used to detect HIV-1 and HIV-2 core antigen in a sample.
Abstract translation: 本发明涉及可用于检测人类免疫缺陷病毒（HIV）的新型抗体。 这些抗体表现出高度的灵敏度，并被认为提供广泛的特异性。 抗体可用于检测样品中的HIV-1和HIV-2核心抗原。
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2.发明申请TRUNCATED HUMAN VITAMIN D BINDING PROTEIN AND MUTATION AND FUSION THEREOF AND RELATED MATERIALS AND METHODS OF USE 审中-公开截短人维生素D结合蛋白及其相关材料及其使用方法
公开(公告)号：WO2013102149A1
公开(公告)日：2013-07-04
申请号：PCT/US2012/072189
申请日：2012-12-28
Applicant: ABBOTT LABORATORIES
Inventor： BECKERT, Christian , BROPHY, Susan, E. , GROTE, Jonathan , HUANG, Dagang , SCHULTESS, Jan , TU, Bailin
CPC classification number: G01N33/82 , C07K14/47 , C07K14/76 , C07K2319/00 , C07K2319/30 , C07K2319/40 , G01N33/543
Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
Abstract translation: 维生素D结合蛋白（DBP），特别是截短的DBP和突变的截短的DBP，以及其融合蛋白，编码相同的核酸分子，载体，宿主细胞和方法，试剂盒和固体支持物，用于确定总量为25 - 羟基维生素D2和25-羟基维生素D3。
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公开(公告)号：WO2010099079A1
公开(公告)日：2010-09-02
申请号：PCT/US2010/024979
申请日：2010-02-23
Applicant: ABBOTT LABORATORIES , BROPHY, Susan E. , TU, Bailin , TYNER, Lowell J. , HUANG, Dagang , ZIEMANN, Robert N.
Inventor： BROPHY, Susan E. , TU, Bailin , HUANG, Dagang , ZIEMANN, Robert N.
CPC classification number: C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
Abstract translation: 本发明涉及肌钙蛋白I的抗体及其使用方法。 特别地，这样的抗体可用于检测患者中的肌钙蛋白I，并且也可用于诊断例如心肌梗死或急性冠状动脉综合征。
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Patent Agency Ranking
公开(公告)号：EP2401292A1
公开(公告)日：2012-01-04
申请号：EP10704731.8
申请日：2010-02-23
Applicant: Abbott Laboratories
Inventor： BROPHY, Susan E. , TU, Bailin , HUANG, Dagang , ZIEMANN, Robert N. , TYNER, Joan, D.
CPC classification number: C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
Abstract: The subject invention relates to antibodies to troponin I as well as methods of use thereof. In particular, such antibodies may be used to detect Troponin I in a patient and may also be used in the diagnosis of, for example, a myocardial infarction or acute coronary syndrome.
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公开(公告)号：EP2609114B1
公开(公告)日：2018-04-11
申请号：EP11749323.9
申请日：2011-08-24
Applicant: ABBOTT LABORATORIES
Inventor： BELK, Jonathan , BROPHY, Susan , HUANG, Dagang , TIEMAN, Bryan , SCHEFFEL, James , TYNER, Joan , ZIEMANN, Robert
CPC classification number: C07K16/1054 , C07K2317/92 , G01N33/56988
Abstract: This invention relates to novel antibodies that can be used in the detection of human immunodeficiency virus (HIV). These antibodies exhibit a high degree of sensitivity and are believed to provide broad range of specificity. The antibodies can be used to detect HIV-1 and HIV-2 core antigen in a sample.
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6.发明公开TRUNCATED HUMAN VITAMIN D BINDING PROTEIN AND MUTATION AND FUSION THEREOF AND RELATED MATERIALS AND METHODS OF USE 审中-公开缩短人体维生素D-结合蛋白，以及融合突变THEREOF及相关材料和使用方法
公开(公告)号：EP2798067A1
公开(公告)日：2014-11-05
申请号：EP12815980.3
申请日：2012-12-28
Applicant: ABBOTT LABORATORIES
Inventor： BECKERT, Christian , BROPHY, Susan, E. , GROTE, Jonathan , HUANG, Dagang , SCHULTESS, Jan , TU, Bailin
CPC classification number: G01N33/82 , C07K14/47 , C07K14/76 , C07K2319/00 , C07K2319/30 , C07K2319/40 , G01N33/543
Abstract: Vitamin D binding proteins (DBP), in particular truncated DBP and mutated, truncated DBP, as well as fusion proteins thereof, nucleic acid molecules encoding same, vectors, host cells, and methods, kits and solid supports for determining the total amount of 25-hydroxy vitamin D2 and 25-hydroxy vitamin D3 in a test sample.
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公开(公告)号：EP2401292B1
公开(公告)日：2014-10-29
申请号：EP10704731.8
申请日：2010-02-23
Applicant: ABBOTT LABORATORIES
Inventor： BROPHY, Susan E. , TU, Bailin , HUANG, Dagang , ZIEMANN, Robert N. , TYNER, Joan, D.
CPC classification number: C07K16/18 , C07K14/4716 , C07K2317/24 , C07K2317/565 , C07K2317/622 , C07K2317/92
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公开(公告)号：EP2609114A1
公开(公告)日：2013-07-03
申请号：EP11749323.9
申请日：2011-08-24
Applicant: Abbott Laboratories
Inventor： BELK, Jonathan , BROPHY, Susan , HUANG, Dagang , TIEMAN, Bryan , SCHEFFEL, James , TYNER, Joan , ZIEMANN, Robert
CPC classification number: C07K16/1054 , C07K2317/92 , G01N33/56988
Abstract: This invention relates to novel antibodies that can be used in the detection of human immunodeficiency virus (HIV). These antibodies exhibit a high degree of sensitivity and are believed to provide broad range of specificity. The antibodies can be used to detect HIV-1 and HIV-2 core antigen in a sample.
Abstract translation: 本发明涉及可用于检测人类免疫缺陷病毒（HIV）的新型抗体。 这些抗体表现出高度的灵敏度，并被认为提供广泛的特异性。 抗体可用于检测样品中的HIV-1和HIV-2核心抗原。
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