Patent search ap:("ABBOTT LABORATORIES") AND inv:"KU Page Yi-Kin"

1.

发明申请
2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES 审中-公开
Title translation: 2'-保护的3'-二甲基氨基甲酸9-ETHEROXIME ERYTHROMYCIN衍生物

公开(公告)号：WO1997036912A1

公开(公告)日：1997-10-09

申请号：PCT/US1997001952

申请日：1997-02-06

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES , YANG, Chengxi , PATEL, Hemantkumar, H. , KU, Yi-Kin , LIU, Jih-Hua

IPC: C07H17/08

CPC classification number: C07H17/08 , Y02P20/55

Abstract: A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.

Abstract translation: 提供了使用2'-保护的9-乙烯基肟红霉素A中间体制备6-O-甲基红霉素A衍生物的方法。 2位的优选保护基是乙酰基。还提供了2'-保护的9-乙酰肟红霉素A衍生物。还公开了抑制在3'胺上形成季盐的方法，而不需要3'N保护基团。

2.

发明授权
2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES 无效
Title translation: 2'-PROTECTED 3'-二甲胺，9-肟醚红霉素A衍生物

公开(公告)号：EP0891370B1

公开(公告)日：2002-12-04

申请号：EP97905824.5

申请日：1997-02-06

Applicant: Abbott Laboratories

Inventor： YANG, Chengxi , PATEL, Hemantkumar, H. , KU, Yi-Kin , LIU, Jih-Hua

IPC: C07H17/08

CPC classification number: C07H17/08 , Y02P20/55

Abstract: A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.

3.

发明公开
2'-PROTECTED 3'-DIMETHYLAMINE, 9-ETHEROXIME ERYTHROMYCIN A DERIVATIVES 无效
Title translation: 2'-PROTECTED 3'-二甲胺，9-肟醚红霉素A衍生物

公开(公告)号：EP0891370A1

公开(公告)日：1999-01-20

申请号：EP97905824.0

申请日：1997-02-06

Applicant: Abbott Laboratories

Inventor： YANG, Chengxi , PATEL, Hemantkumar, H. , KU, Yi-Kin , LIU, Jih-Hua

IPC: C07H17

CPC classification number: C07H17/08 , Y02P20/55

Abstract: A process of preparing a 6-O-methyl erythromycin A derivative using a 2'-protected, 9-etheroxime erythromycin A intermediate is provided. A preferred protecting group for the 2'-position is acetyl. 2'-protected, 9-etheroxime erythromycin A derivatives are also provided. Also disclosed is a method for inhibiting quaternary salt formation at the 3' amine without the need for 3'N-protecting groups.

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